2. Academic Validation
  3. D-lactate dehydrogenase. Substrate specificity and use as a catalyst in the synthesis of homochiral 2-hydroxy acids

D-lactate dehydrogenase. Substrate specificity and use as a catalyst in the synthesis of homochiral 2-hydroxy acids

  • Appl Biochem Biotechnol. 1989 Nov;22(2):169-79. doi: 10.1007/BF02921743.
E S Simon 1,  R Plante,  G M Whitesides
Affiliations

Affiliation

  • 1 Department of Chemistry, Harvard University, Cambridge, MA 02138.
PMID: 2610514 DOI: 10.1007/BF02921743
Abstract

This note compares the substrate specificity of D-lactate dehydrogenase (D-LDH, EC 1.1.1.28) to that of L-lactate dehydrogenase (L-LDH, EC 1.1.1.27), illustrates three procedures that use D-LDH in synthesis and two methods for recycling NADH, and provides experimental details illustrating the use of D-LDH in organic synthesis.

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