2. Academic Validation
  3. Studies on new phosphate ester antifungal antibiotics phoslactomycins. II. Structure elucidation of phoslactomycins A to F

Studies on new phosphate ester antifungal antibiotics phoslactomycins. II. Structure elucidation of phoslactomycins A to F

  • J Antibiot (Tokyo). 1989 Jul;42(7):1026-36. doi: 10.7164/antibiotics.42.1026.
S Fushimi 1,  K Furihata,  H Seto
Affiliations

Affiliation

  • 1 Institute of Applied Microbiology, University of Tokyo, Japan.
PMID: 2753809 DOI: 10.7164/antibiotics.42.1026
Abstract

Phoslactomycins A to F are new antifungal Antibiotics produced by Streptomyces nigrescens SC-273. On the basis of physico-chemical properties and NMR studies, their structures have been determined as shown in Fig. 6. They are characterized by possessing alpha, beta-unsaturated delta-lactone, phosphate ester, conjugated diene and cyclohexane ring moieties. The structural difference between them is ascribed to a substituent bound to the cyclohexane ring.

Figures
Products