2. Academic Validation
  3. Fluorescein as an artificial enzyme to mimic peroxidase

Fluorescein as an artificial enzyme to mimic peroxidase

  • Chem Commun (Camb). 2016 Nov 24;52(96):13912-13915. doi: 10.1039/c6cc07896f.
Li Liu 1,  Ying Shi 2,  Yufang Yang 2,  Menglu Li 2,  Yijuan Long 2,  Yuming Huang 2,  Huzhi Zheng 2
Affiliations

Affiliations

  • 1 Key Laboratory on Luminescent and Real-Time Analytical Chemistry, Ministry of Education, College of Chemistry and Chemical Engineering, Southwest University, Chongqing 400715, P. R. China. ymhuang@swu.edu.cn zhenghz@swu.edu.cn and College of Chemistry and Environmental Science, Qujing Normal University, Qujing, 655011, P. R. China.
  • 2 Key Laboratory on Luminescent and Real-Time Analytical Chemistry, Ministry of Education, College of Chemistry and Chemical Engineering, Southwest University, Chongqing 400715, P. R. China. ymhuang@swu.edu.cn zhenghz@swu.edu.cn.
PMID: 27841375 DOI: 10.1039/c6cc07896f
Abstract

Fluorescein was found to possess intrinsic peroxidase-like activity, which could catalyze the oxidation of 3,3',5,5'-tetramethylbenzidine (TMB) by H2O2 to produce a color reaction. It opens the possibility of using such small molecules as peroxidase-like catalysts.

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