2. Academic Validation
  3. [Effects, in rats, of metapramine and carpipramine on the uptake of catecholamines and serotonin; relationship with 3H-imipramine binding]

[Effects, in rats, of metapramine and carpipramine on the uptake of catecholamines and serotonin; relationship with 3H-imipramine binding]

  • C R Seances Soc Biol Fil. 1986;180(1):43-8.
H Dagonneau,  P Fonlupt,  H Pacheco
PMID: 3017518
Abstract

Carpipramine and metapramine inhibited 3H-imipramine binding both added in vitro and administered to the animal. They were inhibitors of NA uptake and they did not modified 5HT uptake. Only carpipramine affected DA release and uptake.

Figures
Products
  • Cat. No.
    Product Name
    Description
    Target
    Research Area
  • HY-107031
    Antidepressant Agent