2. Academic Validation
  3. Overview of Recent Strategic Advances in Medicinal Chemistry

Overview of Recent Strategic Advances in Medicinal Chemistry

  • J Med Chem. 2019 Nov 14;62(21):9375-9414. doi: 10.1021/acs.jmedchem.9b00359.
Gaochan Wu 1,  Tong Zhao 1,  Dongwei Kang 1,  Jian Zhang 1,  Yuning Song 2,  Vigneshwaran Namasivayam 3,  Jacob Kongsted 4,  Christophe Pannecouque 5,  Erik De Clercq 5,  Vasanthanathan Poongavanam 4,  Xinyong Liu 1,  Peng Zhan 1
Affiliations

Affiliations

  • 1 Department of Medicinal Chemistry, Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences , Shandong University , 44 West Culture Road , 250012 Ji'nan , Shandong , P. R. China.
  • 2 Department of Clinical Pharmacy , Qilu Hospital of Shandong University , 250012 Ji'nan , China.
  • 3 Pharmaceutical Institute, Pharmaceutical Chemistry II , University of Bonn , 53121 Bonn , Germany.
  • 4 Department of Physics, Chemistry, and Pharmacy , University of Southern Denmark , DK-5230 Odense M , Denmark.
  • 5 Rega Institute for Medical Research, Laboratory of Virology and Chemotherapy , K.U. Leuven , Herestraat 49 Postbus 1043 (09.A097) , B-3000 Leuven , Belgium.
PMID: 31050421 DOI: 10.1021/acs.jmedchem.9b00359
Abstract

Introducing novel strategies, concepts, and technologies that speed up drug discovery and the drug development cycle is of great importance both in the highly competitive pharmaceutical industry as well as in academia. This Perspective aims to present a "big-picture" overview of recent strategic innovations in medicinal chemistry and drug discovery.

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