2. Academic Validation
  3. Cytotoxic aromatic triterpenes from Maytenus ilicifolia and Maytenus chuchuhuasca

Cytotoxic aromatic triterpenes from Maytenus ilicifolia and Maytenus chuchuhuasca

  • J Nat Prod. 1994 Dec;57(12):1675-81. doi: 10.1021/np50114a009.
O Shirota 1,  H Morita,  K Takeya,  H Itokawa
Affiliations

Affiliation

  • 1 Department of Pharmacognosy, Tokyo College of Pharmacy, Japan.
PMID: 7714534 DOI: 10.1021/np50114a009
Abstract

The isolation and structure elucidation of four cytotoxic aromatic Triterpenes [1-4] along with three known quinoid Triterpenes [5-7] from the South American medicinal Plants Maytenus ilicifolia and M. chuchuhuasca are described. The structures of these aromatic Triterpenes contained aromatized A rings and C-6 oxygenated B rings, and were elucidated by 1H- and 13C-nmr spectroscopic studies and by X-ray crystallographic analysis of 3.

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