2. Academic Validation
  3. Regulation of cathepsin E expression during human B cell differentiation in vitro

Regulation of cathepsin E expression during human B cell differentiation in vitro

  • Eur J Immunol. 1996 Aug;26(8):1838-43. doi: 10.1002/eji.1830260826.
L Sealy 1,  F Mota,  N Rayment,  P Tatnell,  J Kay,  B Chain
Affiliations

Affiliation

  • 1 Department of Immunology, UCL Medical School, London, GB.
PMID: 8765029 DOI: 10.1002/eji.1830260826
Abstract

Cathepsin E is an aspartic proteinase which has been implicated in antigen processing in the class II major histocompatibility complex pathway. In this study we show that Cathepsin E, measured at both the protein and message level, is up-regulated late in human B cell activation. The implications of this observation in terms of Cathepsin E function are discussed.

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