2. Academic Validation
  3. Exophilin A, a new antibiotic from a marine microorganism Exophiala pisciphila

Exophilin A, a new antibiotic from a marine microorganism Exophiala pisciphila

  • J Antibiot (Tokyo). 1996 Nov;49(11):1105-9. doi: 10.7164/antibiotics.49.1105.
J Doshida 1,  H Hasegawa,  H Onuki,  N Shimidzu
Affiliations

Affiliation

  • 1 Central Research Laboratory, Nippon Suisan Kaisha, Ltd., Tokyo, Japan.
PMID: 8982339 DOI: 10.7164/antibiotics.49.1105
Abstract

Exophilin A, a new Antibacterial compound, was discovered in the culture of the Marine microorganism Exophiala pisciphila NI10102, which was isolated from a marine Sponge Mycale adhaerens. The absolute chemical structure of exophilin A was elucidated as a trimer of (3R,5R)-3,5-dihydroxydecanoic acid by spectroscopic methods and analyses of a degradative product. Exophilin A showed antimicrobial activity against Gram-positive bacteria.

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