2. Academic Validation
  3. New sesquiterpene hydroquinones from a Taiwanese marine sponge Polyfibrospongia australis

New sesquiterpene hydroquinones from a Taiwanese marine sponge Polyfibrospongia australis

  • J Nat Prod. 1997 Feb;60(2):93-7. doi: 10.1021/np9605302.
Y C Shen 1,  P W Hsieh
Affiliations

Affiliation

  • 1 Institute of Marine Resources, National Sun Yat-sen University, Kaohsiung, Taiwan, Republic of China.
PMID: 9051909 DOI: 10.1021/np9605302
Abstract

Two new sesquiterpene hydroquinones, polyfibrospongols A (1) and B (2), were isolated from the Taiwanese marine Sponge Polyfibrospongia australis Lendenfeld (Spongiidae) in addition to the known metabolites, dictyoceratin A (3), ilimaquinone (4), and 5-epi-ilimaquinone (9). The structures of these compounds have been determined mainly on the basis of spectral and chemical methods. Biological testing revealed that compounds 1 and 2 exhibited significant cytotoxicity against human KB-16, A-549, and murine P-388 tumor cell lines.

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