2. Anti-infection
  3. Parasite
  4. MED6-189

MED6-189, a kalihinol analog, disrupts apicoplast function and vesicular trafficking in P. falciparum malaria (IC50 < 50 nM). MED6-189 targets the apicoplast, a nonphotosynthetic plastid found in most Apicomplexa parasites that is crucial for the synthesis of isoprenoids.

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MED6-189 Chemical Structure

MED6-189 Chemical Structure

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MED6-189 Related Antibodies

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Description

MED6-189, a kalihinol analog, disrupts apicoplast function and vesicular trafficking in P. falciparum malaria (IC50 < 50 nM). MED6-189 targets the apicoplast, a nonphotosynthetic plastid found in most Apicomplexa parasites that is crucial for the synthesis of isoprenoids[1].

Molecular Weight

274.40

Formula

C17H26N2O
SMILES

[H][C@]12CC[C@@](C#N)([C@@H]([C@@]1([C@H](CC[C@@]2(C#N)C)C(C)C)[H])O)C
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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MED6-189 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

MED6-189ParasiteInhibitorinhibitorinhibit

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