2. Immunology/Inflammation Metabolic Enzyme/Protease Autophagy Apoptosis
  3. COX MMP Autophagy Apoptosis
  4. Meloxicam sodium

Meloxicam sodium is a non-steroidal anti-inflammatory agent, inhibits COX activity, with IC50s of 0.49 μM and 36.6 μM for COX-2 and COX-1, respectively.

For research use only. We do not sell to patients.

Meloxicam sodium Chemical Structure

Meloxicam sodium Chemical Structure

CAS No. : 71125-39-8

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Meloxicam sodium Related Antibodies

Top Publications Citing Use of Products

    Meloxicam sodium purchased from MedChemExpress. Usage Cited in: Naunyn Schmiedebergs Arch Pharmacol. 2023 Nov 8.  [Abstract]

    Meloxicam (0, 1, 5, 10, 15, 20 μM; 24, 48 h) shows the highest cell viability in human articular chondrocytes at 10 μM.

    View All COX Isoform Specific Products:

    View All Isoforms
    COX COX-1 COX-2 COX-3

    View All MMP Isoform Specific Products:

    View All Isoforms
    MMP-1 MMP-2 MMP-3 MMP-8 MMP-9 MMP-13 MMP-14 MMP-17 ADAM10 ADAM17 MMP-7 MMP-12 MMP-10 MMP ADAM8

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    Description

    Meloxicam sodium is a non-steroidal anti-inflammatory agent, inhibits COX activity, with IC50s of 0.49 μM and 36.6 μM for COX-2 and COX-1, respectively[1].

    IC50 & Target

    COX-2

    0.49 μM (IC50)

    COX-1

    36.6 μM (IC50)

    MMP-2

     

    In Vitro

    Meloxicam sodium (0.25 μg/mL) decreases CF41.Mg cell migration and invasion, induces decrease in MMP-2 expression, and increases β-catenin phophorylation in CF41.Mg cells, but does not affect the CF41.Mg cell apoptosis[2].

    MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

    Meloxicam sodium Related Antibodies
    Clinical Trial
    Molecular Weight

    373.38

    Formula

    C14H12N3NaO4S2
    CAS No.
    SMILES

    O=C(C1=C(O[Na])C2=CC=CC=C2S(N1C)(=O)=O)NC3=NC=C(C)S3
    Shipping

    Room temperature in continental US; may vary elsewhere.
    Storage

    Please store the product under the recommended conditions in the Certificate of Analysis.
    Purity & Documentation
    References
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    Meloxicam sodium Related Classifications

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    Help & FAQs
    • Do most proteins show cross-species activity?

      Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

    Keywords:

    Meloxicam71125-39-8COXMMPAutophagyApoptosisCyclooxygenaseMatrix metalloproteinasesanti-inflammatoryCF41.Mg cellβ-cateninInhibitorinhibitorinhibit

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