1. Immunology/Inflammation Autophagy Apoptosis
  2. COX Autophagy Apoptosis
  3. Meloxicam-d3

Meloxicam-d3 is deuterium labeled Meloxicam. Meloxicam is a non-steroidal antiinflammatory agent, inhibits COX activity, with IC50s of 0.49 µM and 36.6 µM for COX-2 and COX-1, respectively[1].

For research use only. We do not sell to patients.

Meloxicam-d<sub>3</sub> Chemical Structure

Meloxicam-d3 Chemical Structure

CAS No. : 942047-63-4

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1 mg USD 260 In-stock
5 mg USD 660 In-stock
10 mg USD 1120 In-stock
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Based on 1 publication(s) in Google Scholar

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Description

Meloxicam-d3 is deuterium labeled Meloxicam. Meloxicam is a non-steroidal antiinflammatory agent, inhibits COX activity, with IC50s of 0.49 µM and 36.6 µM for COX-2 and COX-1, respectively[1].

Molecular Weight

354.42

Formula

C14H10D3N3O4S2

CAS No.
Unlabeled CAS

71125-38-7

Appearance

Solid

Color

Light yellow to yellow

SMILES

O=C(C1=C(O)C2=CC=CC=C2S(N1C([2H])([2H])[2H])(=O)=O)NC3=NC=C(C)S3

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : ≥ 20 mg/mL (56.43 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

DMF : ≥ 20 mg/mL (56.43 mM)

DMF : ≥ 20 mg/mL (56.43 mM)

DMSO : ≥ 20 mg/mL (56.43 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

DMSO:PBS (pH 7.2) (1:1) : ≥ 0.5 mg/mL (1.41 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.8215 mL 14.1076 mL 28.2151 mL
5 mM 0.5643 mL 2.8215 mL 5.6430 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

V1

=
Concentration (final)

C2

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V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO:PBS (pH 7.2) (1:1) / DMSO / DMF / DMF / DMSO 1 mM 2.8215 mL 14.1076 mL 28.2151 mL 70.5378 mL
DMSO / DMF / DMF / DMSO 5 mM 0.5643 mL 2.8215 mL 5.6430 mL 14.1076 mL
10 mM 0.2822 mL 1.4108 mL 2.8215 mL 7.0538 mL
15 mM 0.1881 mL 0.9405 mL 1.8810 mL 4.7025 mL
20 mM 0.1411 mL 0.7054 mL 1.4108 mL 3.5269 mL
25 mM 0.1129 mL 0.5643 mL 1.1286 mL 2.8215 mL
30 mM 0.0941 mL 0.4703 mL 0.9405 mL 2.3513 mL
40 mM 0.0705 mL 0.3527 mL 0.7054 mL 1.7634 mL
50 mM 0.0564 mL 0.2822 mL 0.5643 mL 1.4108 mL
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Meloxicam-d3
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