2. Anti-infection
  3. HIV
  4. Methyl salvionolate A

Methyl salvionolate A is a potent inhibitor of HIV-1. Methyl salvionolate A inhibits P24 antigen in HIV-1 infected MT-4 cell with an EC50 of 1.62 μg/ml. Methyl salvionolate A also inhibits HIV-1 reverse transcriptase, protease and integrase with IC50s of 50.58, 10.73 and 7.58 μg/ml, respectively.

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Methyl salvionolate A Chemical Structure

Methyl salvionolate A Chemical Structure

CAS No. : 1015171-69-3

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Methyl salvionolate A Related Antibodies

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Description

Methyl salvionolate A is a potent inhibitor of HIV-1. Methyl salvionolate A inhibits P24 antigen in HIV-1 infected MT-4 cell with an EC50 of 1.62 μg/ml. Methyl salvionolate A also inhibits HIV-1 reverse transcriptase, protease and integrase with IC50s of 50.58, 10.73 and 7.58 μg/ml, respectively[1].

Cellular Effect
Cell Line Type Value Description References
MOLM-13 IC50
6.7 μM
Compound: 14
Antiproliferative activity against human MOLM13 cells by Cell-Titer Glo assay
Antiproliferative activity against human MOLM13 cells by Cell-Titer Glo assay
[PMID: 30370766]
MOLM-14 IC50
> 10 μM
Compound: 14
Antiproliferative activity against human MOLM14 cells by Cell-Titer Glo assay
Antiproliferative activity against human MOLM14 cells by Cell-Titer Glo assay
[PMID: 30370766]
MV4-11 IC50
> 10 μM
Compound: 14
Antiproliferative activity against human MV4-11 cells by Cell-Titer Glo assay
Antiproliferative activity against human MV4-11 cells by Cell-Titer Glo assay
[PMID: 30370766]
Molecular Weight

508.47

Formula

C27H24O10
CAS No.
SMILES

OC(C=C1/C=C/C2=C(C=CC(O)=C2O)/C=C/C(O[C@@H](C(OC)=O)CC3=CC(O)=C(C=C3)O)=O)=C(C=C1)O
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Methyl salvionolate A Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Methyl salvionolate A1015171-69-3HIVHuman immunodeficiency virusAnti-HIV-1 activityPolyphenolsMT-4P24 antigenHIV-1 replicative enzymesInhibitorinhibitorinhibit

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