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Metopimazine  (Synonyms: EXP999; RP9965)

Cat. No.: HY-116578 Purity: 98.03%
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Metopimazine (EXP999) is a phenothiazine derivative used to prevent emesis during chemotherapy. Metopimazine belongs to the anti-dopaminergic anti-emetics (ADA) class. Metopimazine can be used for the research of gastroenteritis (GE) .

For research use only. We do not sell to patients.

Metopimazine Chemical Structure

Metopimazine Chemical Structure

CAS No. : 14008-44-7

Size Price Stock Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
 USD 286 In-stock
Solution
10 mM * 1 mL in DMSO USD 286 In-stock
Solid
5 mg USD 260 In-stock
10 mg USD 380 In-stock
25 mg USD 800 In-stock
50 mg USD 1280 In-stock
100 mg USD 2100 In-stock
200 mg   Get quote  
500 mg   Get quote  

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This product is a controlled substance and not for sale in your territory.

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Based on 1 publication(s) in Google Scholar

Other Forms of Metopimazine:

Metopimazine Related Antibodies

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Description

Metopimazine (EXP999) is a phenothiazine derivative used to prevent emesis during chemotherapy. Metopimazine belongs to the anti-dopaminergic anti-emetics (ADA) class. Metopimazine can be used for the research of gastroenteritis (GE) [1].

Molecular Weight

445.60

Formula

C22H27N3O3S2
CAS No.
Appearance

Solid

Color

Off-white to light yellow

SMILES

O=C(N)C1CCN(CC1)CCCN2C3=C(SC4=CC=C(C=C24)S(=O)(C)=O)C=CC=C3
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 50 mg/mL (112.21 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.2442 mL 11.2208 mL 22.4417 mL
5 mM 0.4488 mL 2.2442 mL 4.4883 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.2442 mL 11.2208 mL 22.4417 mL 56.1041 mL
5 mM 0.4488 mL 2.2442 mL 4.4883 mL 11.2208 mL
10 mM 0.2244 mL 1.1221 mL 2.2442 mL 5.6104 mL
15 mM 0.1496 mL 0.7481 mL 1.4961 mL 3.7403 mL
20 mM 0.1122 mL 0.5610 mL 1.1221 mL 2.8052 mL
25 mM 0.0898 mL 0.4488 mL 0.8977 mL 2.2442 mL
30 mM 0.0748 mL 0.3740 mL 0.7481 mL 1.8701 mL
40 mM 0.0561 mL 0.2805 mL 0.5610 mL 1.4026 mL
50 mM 0.0449 mL 0.2244 mL 0.4488 mL 1.1221 mL
60 mM 0.0374 mL 0.1870 mL 0.3740 mL 0.9351 mL
80 mM 0.0281 mL 0.1403 mL 0.2805 mL 0.7013 mL
100 mM 0.0224 mL 0.1122 mL 0.2244 mL 0.5610 mL
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Metopimazine Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Metopimazine14008-44-7EXP999 RP9965EXP 999EXP-999RP9965RP 9965RP-9965Othersanti-dopaminergic anti-emetics (ADA)phenothiazine derivativeemesisgastroenteritis (GE)Inhibitorinhibitorinhibit

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