2. Epigenetics
  3. METTL3
  4. METTL3-IN-5

METTL3-IN-5 (Compound 13) is a METTL3 inhibitor. METTL3-IN-5 inhibits MOLM-13 growth with an IC50 less than 2 μM. METTL3-IN-5 has weak hERG inhibitory activity (IC50 >30 μM). METTL3-IN-5 can be used for AML research.

For research use only. We do not sell to patients.

METTL3-IN-5 Chemical Structure

METTL3-IN-5 Chemical Structure

CAS No. : 2965311-25-3

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METTL3-IN-5 Related Antibodies

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Description

METTL3-IN-5 (Compound 13) is a METTL3 inhibitor. METTL3-IN-5 inhibits MOLM-13 growth with an IC50 less than 2 μM. METTL3-IN-5 has weak hERG inhibitory activity (IC50 >30 μM). METTL3-IN-5 can be used for AML research[1].

IC50 & Target

METTL3[1]
Molecular Weight

451.52

Formula

C23H22FN5O2S
CAS No.
SMILES

O=C1C=C(C(NCC2=CC3=C(C=C(CNCC45CC(C4)(C5)F)N3)S2)=O)N=C6C=CC=CN16
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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METTL3-IN-5 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

METTL3-IN-52965311-25-3METTL3Methyltransferase-like 3AMLhERGcancerInhibitorinhibitorinhibit

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