2. GPCR/G Protein Neuronal Signaling
  3. mGluR
  4. mGluR3 modulator-1

mGluR3 modulator-1 (compound 3) is a mGluR3 modulator, with an EC50 of 1-10 μM in HEK293T-mGluR-Gqi5 Calcium Mobilization Assay.

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mGluR3 modulator-1 Chemical Structure

mGluR3 modulator-1 Chemical Structure

CAS No. : 374548-18-2

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10 mg USD 180 In-stock
25 mg USD 325 In-stock
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Based on 1 publication(s) in Google Scholar

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Description

mGluR3 modulator-1 (compound 3) is a mGluR3 modulator, with an EC50 of 1-10 μM in HEK293T-mGluR-Gqi5 Calcium Mobilization Assay[1].

Molecular Weight

271.36

Formula

C16H21N3O
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

N#CC1=C(N2CCOCC2)N=C(CC)C3=C1CCCC3
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 125 mg/mL (460.64 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.6851 mL 18.4257 mL 36.8514 mL
5 mM 0.7370 mL 3.6851 mL 7.3703 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

V1

=
Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.6851 mL 18.4257 mL 36.8514 mL 92.1285 mL
5 mM 0.7370 mL 3.6851 mL 7.3703 mL 18.4257 mL
10 mM 0.3685 mL 1.8426 mL 3.6851 mL 9.2129 mL
15 mM 0.2457 mL 1.2284 mL 2.4568 mL 6.1419 mL
20 mM 0.1843 mL 0.9213 mL 1.8426 mL 4.6064 mL
25 mM 0.1474 mL 0.7370 mL 1.4741 mL 3.6851 mL
30 mM 0.1228 mL 0.6142 mL 1.2284 mL 3.0710 mL
40 mM 0.0921 mL 0.4606 mL 0.9213 mL 2.3032 mL
50 mM 0.0737 mL 0.3685 mL 0.7370 mL 1.8426 mL
60 mM 0.0614 mL 0.3071 mL 0.6142 mL 1.5355 mL
80 mM 0.0461 mL 0.2303 mL 0.4606 mL 1.1516 mL
100 mM 0.0369 mL 0.1843 mL 0.3685 mL 0.9213 mL
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mGluR3 modulator-1 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

mGluR3 modulator-1374548-18-2mGluRMetabotropic glutamate receptorsmGluR3Calcium MobilizationInhibitorinhibitorinhibit

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