mGluR3 modulator-1

Cat. No.: HY-153132 Purity: 98.67%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

mGluR3 modulator-1 (compound 3) is a mGluR3 modulator, with an EC₅₀ of 1-10 μM in HEK293T-mGluR-Gqi5 Calcium Mobilization Assay.

For research use only. We do not sell to patients.

mGluR3 modulator-1 Chemical Structure

CAS No. : 374548-18-2

Size	Price	Stock	Quantity
5 mg	USD 120	In-stock	Estimated Time of Arrival: December 31
10 mg	USD 180	In-stock	Estimated Time of Arrival: December 31
25 mg	USD 325	In-stock	Estimated Time of Arrival: December 31
50 mg		Get quote
100 mg		Get quote

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Customer Review

Based on 1 publication(s) in Google Scholar

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Biological Activity
Purity & Documentation
References
Customer Review

Description

mGluR3 modulator-1 (compound 3) is a mGluR3 modulator, with an EC₅₀ of 1-10 μM in HEK293T-mGluR-Gqi5 Calcium Mobilization Assay^[1].

Molecular Weight

271.36

Formula

C₁₆H₂₁N₃O

CAS No.

374548-18-2

Appearance

Solid

Color

White to off-white

SMILES

N#CC1=C(N2CCOCC2)N=C(CC)C3=C1CCCC3

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : 125 mg/mL (460.64 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	3.6851 mL	18.4257 mL	36.8514 mL
5 mM	0.7370 mL	3.6851 mL	7.3703 mL
10 mM	0.3685 mL	1.8426 mL	3.6851 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 98.67%

Select Batch:

Data Sheet (270 KB) SDS (251 KB)

COA (250 KB) HNMR (244 KB) LCMS (96 KB)

Handling Instructions (2659 KB)

References

[1]. Justin Potnick, et al. Modulateurs allostériques positifs de mglur3. Patent. WO2014117919.

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	3.6851 mL	18.4257 mL	36.8514 mL	92.1285 mL
	5 mM	0.7370 mL	3.6851 mL	7.3703 mL	18.4257 mL
	10 mM	0.3685 mL	1.8426 mL	3.6851 mL	9.2129 mL
	15 mM	0.2457 mL	1.2284 mL	2.4568 mL	6.1419 mL
	20 mM	0.1843 mL	0.9213 mL	1.8426 mL	4.6064 mL
	25 mM	0.1474 mL	0.7370 mL	1.4741 mL	3.6851 mL
	30 mM	0.1228 mL	0.6142 mL	1.2284 mL	3.0710 mL
	40 mM	0.0921 mL	0.4606 mL	0.9213 mL	2.3032 mL
	50 mM	0.0737 mL	0.3685 mL	0.7370 mL	1.8426 mL
	60 mM	0.0614 mL	0.3071 mL	0.6142 mL	1.5355 mL
	80 mM	0.0461 mL	0.2303 mL	0.4606 mL	1.1516 mL
	100 mM	0.0369 mL	0.1843 mL	0.3685 mL	0.9213 mL