(-)-7-Methoxyrosmanol (Synonyms: (-)-7-O-Methoxyrosmanol)

Cat. No.: HY-111896A: FAQs
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(-)-7-Methoxyrosmanol ((-)-7-O-Methoxyrosmanol) is a phenolic diterpene with antioxidant activity. (-)-7-Methoxyrosmanol is produced from carnosic acid by oxidation and cyclization.

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(-)-7-Methoxyrosmanol Chemical Structure

CAS No. : 24703-38-6

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Description

(-)-7-Methoxyrosmanol ((-)-7-O-Methoxyrosmanol) is a phenolic diterpene with antioxidant activity. (-)-7-Methoxyrosmanol is produced from carnosic acid by oxidation and cyclization^[1]^[2].

Cellular Effect

Cell Line	Type	Value	Description	References
A549	IC₅₀	35.6 μM Compound: 7	Cytotoxicity against human A549 cells at lag phase of growth after 48 hrs by MTT assay Cytotoxicity against human A549 cells at lag phase of growth after 48 hrs by MTT assay	[PMID: 19711987]
A549	IC₅₀	50.8 μM Compound: 7	Cytotoxicity against human A549 cells at exponential phase of growth after 48 hrs by MTT assay Cytotoxicity against human A549 cells at exponential phase of growth after 48 hrs by MTT assay	[PMID: 19711987]
HeLa	IC₅₀	> 60 μM Compound: 7	Cytotoxicity against human HeLa cells at exponential phase of growth after 48 hrs by MTT assay Cytotoxicity against human HeLa cells at exponential phase of growth after 48 hrs by MTT assay	[PMID: 19711987]
HeLa	IC₅₀	40.8 μM Compound: 7	Cytotoxicity against human HeLa cells at lag phase of growth after 48 hrs by MTT assay Cytotoxicity against human HeLa cells at lag phase of growth after 48 hrs by MTT assay	[PMID: 19711987]
MCF7	IC₅₀	23.3 μM Compound: 7	Cytotoxicity against human MCF7 cells at lag phase of growth after 48 hrs by MTT assay Cytotoxicity against human MCF7 cells at lag phase of growth after 48 hrs by MTT assay	[PMID: 19711987]
MCF7	IC₅₀	41.1 μM Compound: 7	Cytotoxicity against human sMCF7 cells at exponential phase of growth after 48 hrs by MTT assay Cytotoxicity against human sMCF7 cells at exponential phase of growth after 48 hrs by MTT assay	[PMID: 19711987]
Vero	IC₅₀	33.9 μM Compound: 7	Cytotoxicity against african green monkey Vero cells at exponential phase of growth after 48 hrs by MTT assay Cytotoxicity against african green monkey Vero cells at exponential phase of growth after 48 hrs by MTT assay	[PMID: 19711987]
Vero	IC₅₀	36.7 μM Compound: 7	Cytotoxicity against african green monkey Vero cells at lag phase of growth after 48 hrs by MTT assay Cytotoxicity against african green monkey Vero cells at lag phase of growth after 48 hrs by MTT assay	[PMID: 19711987]

Molecular Weight

360.44

Formula

C₂₁H₂₈O₅

CAS No.

24703-38-6

SMILES

O=C1[C@]23[C@@](C(C)(CCC3)C)([H])[C@@H]([C@@H](C4=CC(C(C)C)=C(O)C(O)=C42)OC)O1.[Rotation (-)]

Structure Classification

Initial Source

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Jiang Z Y, et al. Perovskatone A: a novel C23 terpenoid from Perovskia atriplicifolia[J]. Tetrahedron letters, 2013, 54(29): 3886-3888.

[2]. Richheimer S L, et al. Antioxidant activity of lipid-soluble phenolic diterpenes from rosemary[J]. Journal of the American Oil Chemists’ Society, 1996, 73(4): 507-514.

(-)-7-Methoxyrosmanol Related Classifications

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass		Concentration		Volume		Molecular Weight *
	=		×		×

The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)	×	Volume _(start)	=	Concentration _(final)	×	Volume _(final)
	×		=		×
C1		V1		C2		V2

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

(-)-7-Methoxyrosmanol24703-38-6(-)-7-O-MethoxyrosmanolOthersInhibitorinhibitorinhibit

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