(-)-KCC2 blocker 1

Cat. No.: HY-18172B Purity: 99.19%: Data Sheet
SDS

COA
Handling Instructions Technical Support

(-)-KCC2 blocker 1 is an enantiomer of KCC2 blocker 1 (HY-18172). KCC2 blocker 1 (compound 13) is an orally active and selective K⁺-Cl^- cotransporter KCC2 blocker with an IC₅₀ of 1 μM.

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(-)-KCC2 blocker 1 Chemical Structure

CAS No. : 1228439-73-3

Size	Stock	Quantity
1 mg	In-stock	Estimated Time of Arrival: December 31
5 mg	In-stock	Estimated Time of Arrival: December 31
10 mg	In-stock	Estimated Time of Arrival: December 31
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Description	(-)-KCC2 blocker 1 is an enantiomer of KCC2 blocker 1 (HY-18172). KCC2 blocker 1 (compound 13) is an orally active and selective K⁺-Cl^- cotransporter KCC2 blocker with an IC₅₀ of 1 μM^[1].
Molecular Weight	415.50
Formula	C₂₂H₂₅NO₅S
CAS No.	1228439-73-3
Appearance	Solid
Color	White to off-white
SMILES	O=C(OCC1=CC=CC=C1)C2(CC3=CC=C(S(=O)(C)=O)C=C3)N(C(C)=O)CCC2
Shipping	Room temperature in continental US; may vary elsewhere.
Storage	4°C, sealed storage, away from moisture and light *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Purity & Documentation	Purity: 99.19% Select Batch: Data Sheet (271 KB) SDS (252 KB) COA (255 KB) HNMR (281 KB) RP-HPLC (256 KB) LCMS (153 KB) Handling Instructions (2659 KB)
References	[1]. Pégurier C, et al. Benzyl prolinate derivatives as novel selective KCC2 blockers. Bioorg Med Chem Lett. 2010 Apr 15;20(8):2542-5. [Content Brief]

(-)-KCC2 blocker 1 Related Classifications

Neurological Disease

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Keywords:

(-)-KCC2 blocker 11228439-73-3Potassium ChannelKcsAInhibitorinhibitorinhibit

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(-)-KCC2 blocker 1

Other Forms of (-)-KCC2 blocker 1:

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