2. Immunology/Inflammation Antibody-drug Conjugate/ADC Related
  3. CD276/B7-H3 ADC Antibody
  4. Mirzotamab

Mirzotamab is an IgG1κ monoclonal antibody targeting to CD276/B7-H3 with anti-tumor activity. Mirzotamab conjugates with Clezutoclax (HY-137774), a BCL inhibitor to form Mirzotamab clezutoclax (HY-P99741), involving in research with taxane research in relapsed/refractory solid tumors. Mirzotamab clezutoclax (ABBV-155) is a targeted antibody drug conjugate (ADC).

For research use only. We do not sell to patients.

CAS No. : 2229859-11-2

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1 mg USD 320 In-stock
5 mg USD 850 In-stock
10 mg USD 1360 In-stock
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Based on 1 publication(s) in Google Scholar

Mirzotamab Related Antibodies

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  • Biological Activity

  • Purity & Documentation

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Description

Mirzotamab is an IgG1κ monoclonal antibody targeting to CD276/B7-H3 with anti-tumor activity. Mirzotamab conjugates with Clezutoclax (HY-137774), a BCL inhibitor to form Mirzotamab clezutoclax (HY-P99741), involving in research with taxane research in relapsed/refractory solid tumors. Mirzotamab clezutoclax (ABBV-155) is a targeted antibody drug conjugate (ADC)[1][2][3].

Isotype

Human IgG1 kappa
Recommend Isotype Controls
Species

Chimeric; Humanized
IC50 & Target

CD276/B7-H3[1]
CAS No.
Appearance

Liquid

Color

Colorless to light yellow

SMILES

[Mirzotamab]
Shipping

Shipping with dry ice.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Format
  • Human IgG1 kappa
Biological Activity
  • Immobilized CD276/B7-H3 Protein, Human can bind Mirzotamab. The EC50 for this effect is 13.63 ng/mL.
Purity & Documentation

Purity: 95.00%

SDS (251 KB)

COA (231 KB)

Inhibitory Antibodies User Guide (602 KB)
References
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Mirzotamab Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Mirzotamab2229859-11-2CD276/B7-H3ADC AntibodyB7 homolog 3 proteinIgG1κ monoclonal antibodyanti-tumor activityMirzotamab clezutoclaxADCInhibitorinhibitorinhibit

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