2. Metabolic Enzyme/Protease
  3. MMP
  4. MMP-9-IN-9

MMP-9-IN-9 (compound 4f) is a slective MMP-9 inhibitor with an IC50 of 5 nM. MMP-9-IN-9 shows selective for MMP-9 over MMP-1 and MMP-13. MMP-9-IN-9 shows strong anti-inflammatory and neuroprotective effects.

For research use only. We do not sell to patients.

MMP-9-IN-9 Chemical Structure

MMP-9-IN-9 Chemical Structure

CAS No. : 206549-55-5

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500 μg In-stock

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MMP-9-IN-9 Related Antibodies

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View All Isoforms
MMP-1 MMP-2 MMP-3 MMP-8 MMP-9 MMP-13 MMP-14 MMP-17 ADAM10 ADAM17 MMP-7 MMP-12 MMP-10 MMP ADAM8

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Description

MMP-9-IN-9 (compound 4f) is a slective MMP-9 inhibitor with an IC50 of 5 nM. MMP-9-IN-9 shows selective for MMP-9 over MMP-1 and MMP-13. MMP-9-IN-9 shows strong anti-inflammatory and neuroprotective effects[1].

IC50 & Target[1]

MMP-9

5 nM (IC50)

MMP-1

1050 nM (IC50)

MMP-13

113 nM (IC50)

Molecular Weight

511.63

Formula

C27H33N3O5S
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C(C1=CC(CN(CC)CC)=CC(C)=C1N(S(=O)(C2=CC=C(C=C2)OC)=O)CC3=CC=CC=C3)NO
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 25 mg/mL (48.86 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.9545 mL 9.7727 mL 19.5454 mL
5 mM 0.3909 mL 1.9545 mL 3.9091 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 97.0%

SDS (251 KB)

COA (256 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.9545 mL 9.7727 mL 19.5454 mL 48.8634 mL
5 mM 0.3909 mL 1.9545 mL 3.9091 mL 9.7727 mL
10 mM 0.1955 mL 0.9773 mL 1.9545 mL 4.8863 mL
15 mM 0.1303 mL 0.6515 mL 1.3030 mL 3.2576 mL
20 mM 0.0977 mL 0.4886 mL 0.9773 mL 2.4432 mL
25 mM 0.0782 mL 0.3909 mL 0.7818 mL 1.9545 mL
30 mM 0.0652 mL 0.3258 mL 0.6515 mL 1.6288 mL
40 mM 0.0489 mL 0.2443 mL 0.4886 mL 1.2216 mL
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MMP-9-IN-9 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

MMP-9-IN-9206549-55-5MMPMatrix metalloproteinasesMMP-9anti-inflammatory and neuroprotective effectsInhibitorinhibitorinhibit

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