2. Anti-infection Cell Cycle/DNA Damage
  3. Bacterial DNA/RNA Synthesis
  4. MMV688844

MMV688844 is a potent Mycobacterium abscessus (Mabs) DNA Gyrase inhibitor with an IC50 value of 2 μM. MMV688844 has bactericidal properties against Mabs bamboo with a MIC50 of 12 μM. MMV688844 can be used for researching anti-bacteria.

For research use only. We do not sell to patients.

MMV688844 Chemical Structure

MMV688844 Chemical Structure

CAS No. : 2650213-59-3

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MMV688844 Related Antibodies

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Description

MMV688844 is a potent Mycobacterium abscessus (Mabs) DNA Gyrase inhibitor with an IC50 value of 2 μM. MMV688844 has bactericidal properties against Mabs bamboo with a MIC50 of 12 μM. MMV688844 can be used for researching anti-bacteria[1].

IC50 & Target

IC50: 2 μM (Mabs DNA Gyrase)[1]
Cellular Effect
Cell Line Type Value Description References
HeLa IC50
> 25 μM
Compound: 47; MMV688844
Cytotoxicity against human HeLa cells assessed as reduction in cell viability after 48 hrs by resazurin dye based fluorescence assay
Cytotoxicity against human HeLa cells assessed as reduction in cell viability after 48 hrs by resazurin dye based fluorescence assay
[PMID: 30647879]
Molecular Weight

424.92

Formula

C23H25ClN4O2
CAS No.
SMILES

O=C(C1CCN(CCC2=CC=C(Cl)C=C2)CC1)NC3=CC=NC4=CC=C(OC)N=C34
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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MMV688844 Related Classifications

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

MMV6888442650213-59-3MMV 688844MMV-688844BacterialDNA/RNA SynthesisAntibacterialMycobacterium abscessusDNA GyraseInhibitorinhibitorinhibit

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