2. JAK/STAT Signaling Epigenetics Stem Cell/Wnt NF-κB Metabolic Enzyme/Protease Immunology/Inflammation Apoptosis Protein Tyrosine Kinase/RTK
  3. JAK NF-κB Reactive Oxygen Species Apoptosis VEGFR c-Myc
  4. Mollugin (Standard)

Mollugin (Standard) is the analytical standard of Mollugin. This product is intended for research and analytical applications. Mollugin is an orally active and potent NF-κB inhibitor. Mollugin induces S-phase arrest of HepG2 cells, and increased intracellular reactive oxygen species (ROS) levels. Mollugin induces DNA damage in HepG2 cells, as well as an increase in the expression of p-H2AX. Mollugin shows anti-cancer effect by inhibiting TNF-α-induced NF-κB activation. Mollugin enhances the osteogenic action of BMP-2 (bone morphogenetic protein 2) via the p38-Smad signaling pathway.

For research use only. We do not sell to patients.

Mollugin (Standard) Chemical Structure

Mollugin (Standard) Chemical Structure

CAS No. : 55481-88-4

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Mollugin (Standard)55481-88-4JAKNF-κBReactive Oxygen SpeciesApoptosisVEGFRc-MycJanus kinaseNuclear factor-κBNuclear factor-kappaBVascular endothelial growth factor receptorMycHepG2 cellsHeLaHep3BHEK293anti-hepatocellularROSLiver cancerDNA damageantitumorH22-tumorInhibitorinhibitorinhibit

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