2. GPCR/G Protein
  3. P2Y Receptor
  4. MRS 2211 sodium hydrate

MRS 2211 sodium hydrate is a competitive P2Y13 receptor antagonist (pIC50= 5.97). MRS 2211 sodium hydrate is highly selective to the P2Y13 receptor, showing more than 20-fold selectivity compared to the P2Y1 and P2Y12 receptors. MRS 2211 sodium hydrate can be used to further investigate the role of the P2Y13 receptor in different physiological and pathological processes, such as its function in blood cells, the nervous system and the immune system.

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MRS 2211 sodium hydrate Chemical Structure

MRS 2211 sodium hydrate Chemical Structure

CAS No. : 1197030-56-0

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5 mg USD 245 In-stock
10 mg USD 390 In-stock
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MRS 2211 sodium hydrate Related Antibodies

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Description

MRS 2211 sodium hydrate is a competitive P2Y13 receptor antagonist (pIC50= 5.97). MRS 2211 sodium hydrate is highly selective to the P2Y13 receptor, showing more than 20-fold selectivity compared to the P2Y1 and P2Y12 receptors. MRS 2211 sodium hydrate can be used to further investigate the role of the P2Y13 receptor in different physiological and pathological processes, such as its function in blood cells, the nervous system and the immune system[1].

Molecular Weight

470.69

Formula

C14H13ClN4NaO9P
CAS No.
Appearance

Solid

Color

Brown to reddish brown

SMILES

O=CC1=C(COP(O)(O[Na])=O)C(/N=N/C2=CC([N+]([O-])=O)=CC=C2Cl)=NC(C)=C1O.[H]O[H]
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

H2O : 32.95 mg/mL (70.00 mM; Need ultrasonic and warming)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.1245 mL 10.6227 mL 21.2454 mL
5 mM 0.4249 mL 2.1245 mL 4.2491 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

V1

=
Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 2.1245 mL 10.6227 mL 21.2454 mL 53.1135 mL
5 mM 0.4249 mL 2.1245 mL 4.2491 mL 10.6227 mL
10 mM 0.2125 mL 1.0623 mL 2.1245 mL 5.3114 mL
15 mM 0.1416 mL 0.7082 mL 1.4164 mL 3.5409 mL
20 mM 0.1062 mL 0.5311 mL 1.0623 mL 2.6557 mL
25 mM 0.0850 mL 0.4249 mL 0.8498 mL 2.1245 mL
30 mM 0.0708 mL 0.3541 mL 0.7082 mL 1.7705 mL
40 mM 0.0531 mL 0.2656 mL 0.5311 mL 1.3278 mL
50 mM 0.0425 mL 0.2125 mL 0.4249 mL 1.0623 mL
60 mM 0.0354 mL 0.1770 mL 0.3541 mL 0.8852 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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MRS 2211 sodium hydrate Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

MRS 2211 sodium1197030-56-0P2Y ReceptorCompetitive antagonisthighly selectiveP2Y13nervous systemimmune systemInhibitorinhibitorinhibit

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