2. GPCR/G Protein NF-κB Stem Cell/Wnt MAPK/ERK Pathway Apoptosis
  3. P2Y Receptor NF-κB ERK Apoptosis
  4. MRS2693 ammonium

MRS2693 ammonium is the ammonium dalt form of MRS2693 (HY-117356). MRS2693 ammonium is a selective agonist for P2Y6 with an EC50 of 0.015 μM. MRS2693 ammonium protects C2C12 skeletal muscle cells from TNFα-induced apoptosis. MRS2693 ammonium reduces the activation of NF-kB, activates the ERK1/2 pathway, and has a cytoprotective effect on mouse ischemia-reperfusion injury model[2].

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MRS2693 ammonium Chemical Structure

MRS2693 ammonium Chemical Structure

CAS No. : 911391-37-2

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Other Forms of MRS2693 ammonium:

MRS2693 ammonium Related Antibodies

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Description

MRS2693 ammonium is the ammonium dalt form of MRS2693 (HY-117356). MRS2693 ammonium is a selective agonist for P2Y6 with an EC50 of 0.015 μM. MRS2693 ammonium protects C2C12 skeletal muscle cells from TNFα-induced apoptosis. MRS2693 ammonium reduces the activation of NF-kB, activates the ERK1/2 pathway, and has a cytoprotective effect on mouse ischemia-reperfusion injury model[1][2].

IC50 & Target

P2Y6 Receptor

0.015 μM (EC50)

Molecular Weight

581.15

Formula

C9H22IN5O12P2
CAS No.
SMILES

O[C@H]1[C@@H](O)[C@H](N2C(NC(C(I)=C2)=O)=O)O[C@@H]1COP(O)(OP(O)(O)=O)=O.N.N.N
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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MRS2693 ammonium Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

MRS2693911391-37-2MRS 2693MRS-2693P2Y ReceptorNF-κBERKApoptosisNuclear factor-κBNuclear factor-kappaBExtracellular signal regulated kinasesC2C12ischemiaC57BL6 mouseskeletal muscle injuryInhibitorinhibitorinhibit

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MRS2693 ammonium
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HY-117356A
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