MurA-IN-4

Cat. No.: HY-21745 Purity: ≥98.0%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

MurA-IN-4 has antibacterial activity and is a MurA inhibitor that inhibits bacterial cell wall synthesis.

For research use only. We do not sell to patients.

MurA-IN-4 Chemical Structure

CAS No. : 318280-69-2

Size	Price	Stock	Quantity
100 mg	USD 50	In-stock	Estimated Time of Arrival: December 31
200 mg		Get quote
500 mg		Get quote

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Biological Activity
Purity & Documentation
References
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Description

MurA-IN-4 has antibacterial activity and is a MurA inhibitor that inhibits bacterial cell wall synthesis^[1].

Molecular Weight

205.64

Formula

C₈H₁₂ClNO₃

CAS No.

318280-69-2

Appearance

Solid

Color

White to off-white

SMILES

O=C(C1CCN(C(CCl)=O)CC1)O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : ≥ 100 mg/mL (486.29 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	4.8629 mL	24.3143 mL	48.6287 mL
5 mM	0.9726 mL	4.8629 mL	9.7257 mL
10 mM	0.4863 mL	2.4314 mL	4.8629 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: ≥98.0%

Select Batch:

Data Sheet (266 KB) SDS (393 KB)

COA (245 KB) HNMR (240 KB)

Handling Instructions (2659 KB)

References

[1]. Grabrijan K, et al. Covalent inhibitors of bacterial peptidoglycan biosynthesis enzyme MurA with chloroacetamide warhead. Eur J Med Chem. 2022 Dec 5;243:114752. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	4.8629 mL	24.3143 mL	48.6287 mL	121.5717 mL
	5 mM	0.9726 mL	4.8629 mL	9.7257 mL	24.3143 mL
	10 mM	0.4863 mL	2.4314 mL	4.8629 mL	12.1572 mL
	15 mM	0.3242 mL	1.6210 mL	3.2419 mL	8.1048 mL
	20 mM	0.2431 mL	1.2157 mL	2.4314 mL	6.0786 mL
	25 mM	0.1945 mL	0.9726 mL	1.9451 mL	4.8629 mL
	30 mM	0.1621 mL	0.8105 mL	1.6210 mL	4.0524 mL
	40 mM	0.1216 mL	0.6079 mL	1.2157 mL	3.0393 mL
	50 mM	0.0973 mL	0.4863 mL	0.9726 mL	2.4314 mL
	60 mM	0.0810 mL	0.4052 mL	0.8105 mL	2.0262 mL
	80 mM	0.0608 mL	0.3039 mL	0.6079 mL	1.5196 mL
	100 mM	0.0486 mL	0.2431 mL	0.4863 mL	1.2157 mL

MurA-IN-4 Related Classifications

Infection

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

MurA-IN-4318280-69-2Bacterialantibacterial activityInhibitorinhibitorinhibit

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