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  4. MuRF1-IN-2

MuRF1-IN-2 (Example 3) is a MuRF1 inhibitor. MuRF1-IN-2 can be used for research of muscle wasting conditions, of skeletal or cardial muscle atrophy.

For research use only. We do not sell to patients.

MuRF1-IN-2 Chemical Structure

MuRF1-IN-2 Chemical Structure

CAS No. : 937891-74-2

Size Price Stock Quantity
10 mg USD 40 In-stock
25 mg USD 78 In-stock
50 mg USD 125 In-stock
100 mg USD 200 In-stock
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MuRF1-IN-2 Related Antibodies

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Description

MuRF1-IN-2 (Example 3) is a MuRF1 inhibitor. MuRF1-IN-2 can be used for research of muscle wasting conditions, of skeletal or cardial muscle atrophy[1].

IC50 & Target

MuRF1[1]
Molecular Weight

438.43

Formula

C23H22N2O7
CAS No.
Appearance

Solid

Color

Off-white to light brown

SMILES

O=C(OC(C)C(NC(NC)=O)=O)C1=CC=C(COC2=CC(O3)=C(C=C2)C(C)=CC3=O)C=C1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 50 mg/mL (114.04 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.2809 mL 11.4043 mL 22.8087 mL
5 mM 0.4562 mL 2.2809 mL 4.5617 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.2809 mL 11.4043 mL 22.8087 mL 57.0216 mL
5 mM 0.4562 mL 2.2809 mL 4.5617 mL 11.4043 mL
10 mM 0.2281 mL 1.1404 mL 2.2809 mL 5.7022 mL
15 mM 0.1521 mL 0.7603 mL 1.5206 mL 3.8014 mL
20 mM 0.1140 mL 0.5702 mL 1.1404 mL 2.8511 mL
25 mM 0.0912 mL 0.4562 mL 0.9123 mL 2.2809 mL
30 mM 0.0760 mL 0.3801 mL 0.7603 mL 1.9007 mL
40 mM 0.0570 mL 0.2851 mL 0.5702 mL 1.4255 mL
50 mM 0.0456 mL 0.2281 mL 0.4562 mL 1.1404 mL
60 mM 0.0380 mL 0.1901 mL 0.3801 mL 0.9504 mL
80 mM 0.0285 mL 0.1426 mL 0.2851 mL 0.7128 mL
100 mM 0.0228 mL 0.1140 mL 0.2281 mL 0.5702 mL
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MuRF1-IN-2 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

MuRF1-IN-2937891-74-2Othersmuscle wasting conditionsskeletal atrophycardial muscle atrophyInhibitorinhibitorinhibit

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