2. Peptides
  3. Peptide and Derivatives
  4. Peptide Epitopes
  5. Myhc-α(334–352)

Myhc-α(334–352) is a sequence fragment of amino acid residues 334 to 352 of cardiac myosin heavy chain α. Myhc-α(334–352) is an immunodominant epitope that can induce autoimmune reactions in A/J mice, leading to the occurrence of myocarditis. Myhc-α(334–352) can be used to study the autoimmune pathways of myocarditis and dilated cardiomyopathy.

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Myhc-α(334–352) Chemical Structure

Myhc-α(334–352) Chemical Structure

CAS No. : 171675-09-5

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Myhc-α(334–352) Related Antibodies

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Description

Myhc-α(334–352) is a sequence fragment of amino acid residues 334 to 352 of cardiac myosin heavy chain α. Myhc-α(334–352) is an immunodominant epitope that can induce autoimmune reactions in A/J mice, leading to the occurrence of myocarditis. Myhc-α(334–352) can be used to study the autoimmune pathways of myocarditis and dilated cardiomyopathy[1].

Molecular Weight

2077.25

Formula

C94H141N21O32
CAS No.
Appearance

Solid

Color

White to off-white

Sequence

Asp-Ser-Ala-Phe-Asp-Val-Leu-Ser-Phe-Thr-Ala-Glu-Glu-Lys-Ala-Gly-Val-Tyr-Lys
Sequence Shortening

DSAFDVLSFTAEEKAGVYK
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : 50 mg/mL (24.07 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.4814 mL 2.4070 mL 4.8141 mL
5 mM 0.0963 mL 0.4814 mL 0.9628 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 0.4814 mL 2.4070 mL 4.8141 mL 12.0351 mL
5 mM 0.0963 mL 0.4814 mL 0.9628 mL 2.4070 mL
10 mM 0.0481 mL 0.2407 mL 0.4814 mL 1.2035 mL
15 mM 0.0321 mL 0.1605 mL 0.3209 mL 0.8023 mL
20 mM 0.0241 mL 0.1204 mL 0.2407 mL 0.6018 mL
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Myhc-α(334–352) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Myhc-α(334–352)171675-09-5OthersCardiac myosinmyocarditisautoimmune wayimmunodominant epitopeInhibitorinhibitorinhibit

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