2. Membrane Transporter/Ion Channel Neuronal Signaling
  3. nAChR
  4. Myosmine-d4

Myosmine-d4 is the deuterium labeled Myosmine. Myosmine, a specific tobacco alkaloid in nuts and nut products, has low affinity for a4b2 nicotinic acetylcholinergic receptors (nAChR) with a Ki of 3300 nM[1][2].

For research use only. We do not sell to patients.

Myosmine-d<sub>4</sub> Chemical Structure

Myosmine-d4 Chemical Structure

CAS No. : 66148-17-2

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5 mg USD 270 In-stock
10 mg USD 430 In-stock
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Based on 1 publication(s) in Google Scholar

Other Forms of Myosmine-d4:

Myosmine-d4 Related Antibodies

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Description

Myosmine-d4 is the deuterium labeled Myosmine. Myosmine, a specific tobacco alkaloid in nuts and nut products, has low affinity for a4b2 nicotinic acetylcholinergic receptors (nAChR) with a Ki of 3300 nM[1][2].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Myosmine-d4 Related Antibodies
Molecular Weight

150.21

Formula

C9H6D4N2
CAS No.
Unlabeled CAS

532-12-7
Appearance

Solid

Color

Brown to reddish brown

SMILES

[2H]C1=C(C2=NCCC2)C([2H])=C([2H])C([2H])=N1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

H2O : ≥ 100 mg/mL (665.73 mM)

DMSO : 100 mg/mL (665.73 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

H2O : ≥ 100 mg/mL (665.73 mM)

DMSO : 100 mg/mL (665.73 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 6.6573 mL 33.2867 mL 66.5735 mL
5 mM 1.3315 mL 6.6573 mL 13.3147 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

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Volume (start)

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=
Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation

Purity: ≥98.0%

COA (252 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O / DMSO / H2O / DMSO 1 mM 6.6573 mL 33.2867 mL 66.5735 mL 166.4337 mL
5 mM 1.3315 mL 6.6573 mL 13.3147 mL 33.2867 mL
10 mM 0.6657 mL 3.3287 mL 6.6573 mL 16.6434 mL
15 mM 0.4438 mL 2.2191 mL 4.4382 mL 11.0956 mL
20 mM 0.3329 mL 1.6643 mL 3.3287 mL 8.3217 mL
25 mM 0.2663 mL 1.3315 mL 2.6629 mL 6.6573 mL
30 mM 0.2219 mL 1.1096 mL 2.2191 mL 5.5478 mL
40 mM 0.1664 mL 0.8322 mL 1.6643 mL 4.1608 mL
50 mM 0.1331 mL 0.6657 mL 1.3315 mL 3.3287 mL
60 mM 0.1110 mL 0.5548 mL 1.1096 mL 2.7739 mL
80 mM 0.0832 mL 0.4161 mL 0.8322 mL 2.0804 mL
100 mM 0.0666 mL 0.3329 mL 0.6657 mL 1.6643 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Myosmine-d4 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Myosmine-d466148-17-2nAChRNicotinic acetylcholine receptorsInhibitorinhibitorinhibit

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