2. Metabolic Enzyme/Protease Neuronal Signaling Protein Tyrosine Kinase/RTK
  3. Endogenous Metabolite Trk Receptor
  4. N-Acetyl-5-hydroxytryptamine-d3

N-Acetyl-5-hydroxytryptamine-d3  (Synonyms: N-Acetylserotonin-d3; Normelatonin-d3; O-Demethylmelatonin-d3)

Cat. No.: HY-107854S Purity: ≥98.0%
SDS COA Handling Instructions

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N-Acetyl-5-hydroxytryptamine-d3 is the deuterium labeled N-Acetyl-5-hydroxytryptamine. N-Acetyl-5-hydroxytryptamine is a Melatonin precursor, and that it can potently activate TrkB receptor[1][2].

For research use only. We do not sell to patients.

N-Acetyl-5-hydroxytryptamine-d<sub>3</sub> Chemical Structure

N-Acetyl-5-hydroxytryptamine-d3 Chemical Structure

CAS No. : 2001098-07-1

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Based on 1 publication(s) in Google Scholar

Other Forms of N-Acetyl-5-hydroxytryptamine-d3:

N-Acetyl-5-hydroxytryptamine-d3 Related Antibodies

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Description

N-Acetyl-5-hydroxytryptamine-d3 is the deuterium labeled N-Acetyl-5-hydroxytryptamine. N-Acetyl-5-hydroxytryptamine is a Melatonin precursor, and that it can potently activate TrkB receptor[1][2].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

N-Acetyl-5-hydroxytryptamine-d3 Related Antibodies
Molecular Weight

221.27

Formula

C12H11D3N2O2
CAS No.
Unlabeled CAS

1210-83-9
Appearance

Solid

Color

White to off-white

SMILES

[2H]C([2H])([2H])C(NCCC(C1=C2)=CNC1=CC=C2O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (451.94 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

DMSO : 100 mg/mL (451.94 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.5194 mL 22.5968 mL 45.1937 mL
5 mM 0.9039 mL 4.5194 mL 9.0387 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: ≥98.0%

SDS (252 KB)

COA (249 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO / DMSO 1 mM 4.5194 mL 22.5968 mL 45.1937 mL 112.9841 mL
5 mM 0.9039 mL 4.5194 mL 9.0387 mL 22.5968 mL
10 mM 0.4519 mL 2.2597 mL 4.5194 mL 11.2984 mL
15 mM 0.3013 mL 1.5065 mL 3.0129 mL 7.5323 mL
20 mM 0.2260 mL 1.1298 mL 2.2597 mL 5.6492 mL
25 mM 0.1808 mL 0.9039 mL 1.8077 mL 4.5194 mL
30 mM 0.1506 mL 0.7532 mL 1.5065 mL 3.7661 mL
40 mM 0.1130 mL 0.5649 mL 1.1298 mL 2.8246 mL
50 mM 0.0904 mL 0.4519 mL 0.9039 mL 2.2597 mL
60 mM 0.0753 mL 0.3766 mL 0.7532 mL 1.8831 mL
80 mM 0.0565 mL 0.2825 mL 0.5649 mL 1.4123 mL
100 mM 0.0452 mL 0.2260 mL 0.4519 mL 1.1298 mL
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N-Acetyl-5-hydroxytryptamine-d3 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

N-Acetyl-5-hydroxytryptamine-d32001098-07-1N-Acetylserotonin-d3Normelatonin-d3O-Demethylmelatonin-d3Endogenous MetaboliteTrk ReceptorTropomyosin related kinase receptorInhibitorinhibitorinhibit

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