N-Acetyl-L-glutamic acid-d₅

Name: N-Acetyl-L-glutamic acid-d 5
Brand: MedChemExpress
SKU: HY-W015240S
Rating: 4.5 (1 reviews)

Cat. No.: HY-W015240S Purity: 99.71%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

N-Acetyl-L-glutamic acid-d₅ is the deuterium labeled N-Acetyl-L-glutamic acid. N-Acetyl-L-glutamic acid, a N-acyl-L-amino acid, is a component of animal cell culturing media. N-Acetyl-L-glutamic acid is a metabolite of Saccharomyces cerevisiae and human[1].

For research use only. We do not sell to patients.

N-Acetyl-L-glutamic acid-d<sub>5</sub> Chemical Structure

N-Acetyl-L-glutamic acid-d₅ Chemical Structure

Size	Price	Stock	Quantity
1 mg	USD 168	In-stock	Estimated Time of Arrival: December 31
5 mg	USD 420	In-stock	Estimated Time of Arrival: December 31
10 mg		Get quote
50 mg		Get quote

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Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of N-Acetyl-L-glutamic acid-d₅:

N-Acetyl-L-glutamic acid Get quote

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Biological Activity
Purity & Documentation
References
Customer Review

Description

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

194.20

Formula

C₇H₆D₅NO₅

Appearance

Solid

Color

White to off-white

SMILES

O=C(O)C([2H])([2H])C([2H])([2H])[C@](C(O)=O)([2H])NC(C)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL (514.93 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	5.1493 mL	25.7467 mL	51.4933 mL
5 mM	1.0299 mL	5.1493 mL	10.2987 mL
10 mM	0.5149 mL	2.5747 mL	5.1493 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 99.71%

Select Batch:

Data Sheet (274 KB) SDS (251 KB)

COA (253 KB) HNMR (576 KB) RP-HPLC (621 KB)

Handling Instructions (2659 KB)

References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]

[2]. M Hashimoto, et al. Animal cell culturing media containing N-acetyl-L-glutamic acid. Patent.

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	5.1493 mL	25.7467 mL	51.4933 mL	128.7333 mL
	5 mM	1.0299 mL	5.1493 mL	10.2987 mL	25.7467 mL
	10 mM	0.5149 mL	2.5747 mL	5.1493 mL	12.8733 mL
	15 mM	0.3433 mL	1.7164 mL	3.4329 mL	8.5822 mL
	20 mM	0.2575 mL	1.2873 mL	2.5747 mL	6.4367 mL
	25 mM	0.2060 mL	1.0299 mL	2.0597 mL	5.1493 mL
	30 mM	0.1716 mL	0.8582 mL	1.7164 mL	4.2911 mL
	40 mM	0.1287 mL	0.6437 mL	1.2873 mL	3.2183 mL
	50 mM	0.1030 mL	0.5149 mL	1.0299 mL	2.5747 mL
	60 mM	0.0858 mL	0.4291 mL	0.8582 mL	2.1456 mL
	80 mM	0.0644 mL	0.3218 mL	0.6437 mL	1.6092 mL
	100 mM	0.0515 mL	0.2575 mL	0.5149 mL	1.2873 mL