2. Others Metabolic Enzyme/Protease
  3. Isotope-Labeled Compounds Endogenous Metabolite
  4. N-Acetyl-L-tyrosine-d3

N-Acetyl-L-tyrosine-d3 is the deuterium labeled N-Acetyl-L-tyrosine. N-Acetyl-L-tyrosine originates from tyrosine through an AA acetylase, is associated with aromatic L-amino acid decarboxylase deficiency and tyrosinemia I.

For research use only. We do not sell to patients.

N-Acetyl-L-tyrosine-d<sub>3</sub> Chemical Structure

N-Acetyl-L-tyrosine-d3 Chemical Structure

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1 mg USD 200 In-stock
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Based on 1 publication(s) in Google Scholar

Other Forms of N-Acetyl-L-tyrosine-d3:

N-Acetyl-L-tyrosine-d3 Related Antibodies

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  • Biological Activity

  • Purity & Documentation

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Description

N-Acetyl-L-tyrosine-d3 is the deuterium labeled N-Acetyl-L-tyrosine. N-Acetyl-L-tyrosine originates from tyrosine through an AA acetylase, is associated with aromatic L-amino acid decarboxylase deficiency and tyrosinemia I.

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

N-Acetyl-L-tyrosine-d3 Related Antibodies
Molecular Weight

226.24

Formula

C11H10D3NO4
Appearance

Solid

Color

White to off-white

SMILES

OC1=CC=C(C=C1)C[C@@H](C(O)=O)NC(C([2H])([2H])[2H])=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

H2O : 100 mg/mL (442.01 mM; Need ultrasonic)

DMSO : 100 mg/mL (442.01 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

H2O : 100 mg/mL (442.01 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.4201 mL 22.1004 mL 44.2008 mL
5 mM 0.8840 mL 4.4201 mL 8.8402 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O / DMSO / H2O 1 mM 4.4201 mL 22.1004 mL 44.2008 mL 110.5021 mL
5 mM 0.8840 mL 4.4201 mL 8.8402 mL 22.1004 mL
10 mM 0.4420 mL 2.2100 mL 4.4201 mL 11.0502 mL
15 mM 0.2947 mL 1.4734 mL 2.9467 mL 7.3668 mL
20 mM 0.2210 mL 1.1050 mL 2.2100 mL 5.5251 mL
25 mM 0.1768 mL 0.8840 mL 1.7680 mL 4.4201 mL
30 mM 0.1473 mL 0.7367 mL 1.4734 mL 3.6834 mL
40 mM 0.1105 mL 0.5525 mL 1.1050 mL 2.7626 mL
50 mM 0.0884 mL 0.4420 mL 0.8840 mL 2.2100 mL
60 mM 0.0737 mL 0.3683 mL 0.7367 mL 1.8417 mL
80 mM 0.0553 mL 0.2763 mL 0.5525 mL 1.3813 mL
100 mM 0.0442 mL 0.2210 mL 0.4420 mL 1.1050 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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N-Acetyl-L-tyrosine-d3 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

N-Acetyl-L-tyrosine-d3Isotope-Labeled CompoundsEndogenous MetaboliteInhibitorinhibitorinhibit

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