1. MAPK/ERK Pathway NF-κB Metabolic Enzyme/Protease
  2. MAP3K p38 MAPK JNK NF-κB Endogenous Metabolite
  3. N-Acetylgalactosaminyltransferase 4

N-Acetylgalactosaminyltransferase 4  (Synonyms: GALNT4)

Cat. No.: HY-E70291
Handling Instructions

N-Acetylgalactosaminyltransferase 4 (GALNT4) is a glycosyltransferase capable of inhibiting the activation of ASK1. By directly binding to ASK1, N-Acetylgalactosaminyltransferase 4 suppresses its N-terminal dimerization and subsequent phosphorylation, leading to robust inactivation of downstream JNK/p38 and NF-κB signals, and thereby improving the prognosis of liver surgery.

For research use only. We do not sell to patients.

N-Acetylgalactosaminyltransferase 4 Chemical Structure

N-Acetylgalactosaminyltransferase 4 Chemical Structure

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Description

N-Acetylgalactosaminyltransferase 4 (GALNT4) is a glycosyltransferase capable of inhibiting the activation of ASK1. By directly binding to ASK1, N-Acetylgalactosaminyltransferase 4 suppresses its N-terminal dimerization and subsequent phosphorylation, leading to robust inactivation of downstream JNK/p38 and NF-κB signals, and thereby improving the prognosis of liver surgery[1].

IC50 & Target

ASK1

 

SMILES

[N-Acetylgalactosaminyltransferase 4]

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Please store the product under the recommended conditions in the Certificate of Analysis.

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    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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N-Acetylgalactosaminyltransferase 4
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HY-E70291
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