2. MAPK/ERK Pathway NF-κB Metabolic Enzyme/Protease
  3. MAP3K p38 MAPK JNK NF-κB Endogenous Metabolite
  4. N-Acetylgalactosaminyltransferase 4

N-Acetylgalactosaminyltransferase 4  (Synonyms: GALNT4)

Cat. No.: HY-E70291
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N-Acetylgalactosaminyltransferase 4 (GALNT4) is a glycosyltransferase capable of inhibiting the activation of ASK1. By directly binding to ASK1, N-Acetylgalactosaminyltransferase 4 suppresses its N-terminal dimerization and subsequent phosphorylation, leading to robust inactivation of downstream JNK/p38 and NF-κB signals, and thereby improving the prognosis of liver surgery.

For research use only. We do not sell to patients.

N-Acetylgalactosaminyltransferase 4 Chemical Structure

N-Acetylgalactosaminyltransferase 4 Chemical Structure

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N-Acetylgalactosaminyltransferase 4 Related Antibodies

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Description

N-Acetylgalactosaminyltransferase 4 (GALNT4) is a glycosyltransferase capable of inhibiting the activation of ASK1. By directly binding to ASK1, N-Acetylgalactosaminyltransferase 4 suppresses its N-terminal dimerization and subsequent phosphorylation, leading to robust inactivation of downstream JNK/p38 and NF-κB signals, and thereby improving the prognosis of liver surgery[1].

IC50 & Target

ASK1

 

SMILES

[N-Acetylgalactosaminyltransferase 4]
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N-Acetylgalactosaminyltransferase 4 Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

N-Acetylgalactosaminyltransferase 4GALNT4GALNT 4GALNT-4MAP3Kp38 MAPKJNKNF-κBEndogenous MetaboliteMAP kinase kinase kinase, MEKK, MAPKKKc-Jun N-terminal kinaseNuclear factor-κBNuclear factor-kappaBliver ischemia-reperfusion injuryInhibitorinhibitorinhibit

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