2. Membrane Transporter/Ion Channel Neuronal Signaling
  3. nAChR
  4. N-Biotinyl p-aminophenyl arsenic acid

N-Biotinyl p-aminophenyl arsenic acid 

Cat. No.: HY-W741573 Purity: 98.13%
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N-Biotinyl p-aminophenyl arsenic acid is a bifunctional reagent that can bind to both streptavidin and dithiols. N-Biotinyl p-aminophenyl arsenic acid decreases the Rbungarotoxin-binding sites in reduced Torpedo nicotinic receptors (IC50 is 10-300 nM), and protects the receptor from irreversible alkylation by bromoacetylcholine.

For research use only. We do not sell to patients.

N-Biotinyl p-aminophenyl arsenic acid Chemical Structure

N-Biotinyl p-aminophenyl arsenic acid Chemical Structure

CAS No. : 212391-23-6

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1 mg USD 143 In-stock
5 mg USD 330 In-stock
10 mg USD 600 In-stock
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N-Biotinyl p-aminophenyl arsenic acid Related Antibodies

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Description

N-Biotinyl p-aminophenyl arsenic acid is a bifunctional reagent that can bind to both streptavidin and dithiols. N-Biotinyl p-aminophenyl arsenic acid decreases the Rbungarotoxin-binding sites in reduced Torpedo nicotinic receptors (IC50 is 10-300 nM), and protects the receptor from irreversible alkylation by bromoacetylcholine[1].

Molecular Weight

427.35

Formula

C16H22AsN3O4S
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=[AsH](O)C(C=C1)=CC=C1NC(CCCC[C@H]2[C@]3([H])[C@](NC(N3)=O)([H])CS2)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 10 mg/mL (23.40 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.3400 mL 11.7000 mL 23.4000 mL
5 mM 0.4680 mL 2.3400 mL 4.6800 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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C2

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V2

In Vivo Dissolution Calculator
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Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.3400 mL 11.7000 mL 23.4000 mL 58.5001 mL
5 mM 0.4680 mL 2.3400 mL 4.6800 mL 11.7000 mL
10 mM 0.2340 mL 1.1700 mL 2.3400 mL 5.8500 mL
15 mM 0.1560 mL 0.7800 mL 1.5600 mL 3.9000 mL
20 mM 0.1170 mL 0.5850 mL 1.1700 mL 2.9250 mL
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N-Biotinyl p-aminophenyl arsenic acid Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

N-Biotinyl p-aminophenyl arsenic acid212391-23-6nAChRNicotinic acetylcholine receptorsInhibitorinhibitorinhibit

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