2. Anti-infection
  3. Bacterial
  4. N-Butanoyl-DL-homoserine lactone

N-Butanoyl-DL-homoserine lactone  (Synonyms: (Rac)-C4-HSL)

Cat. No.: HY-113764 Purity: ≥98.0%
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N-Butanoyl-DL-homoserine lactone ((Rac)-C4-HSL) is a racemic mixture of N-Butanoyl-D-homoserine lactone and N-Butanoyl-L-homoserine lactone. N-Butanoyl-L-homoserine lactone is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). N-Butanoyl-L-homoserine lactone has antibacterial activity and is used in antibacterial biofilm. N-Butanoyl-L-homoserine lactone aptamers blocks qurom sensing and inhibits biofilm formation in Pseudomonas aeruginosa.

For research use only. We do not sell to patients.

N-Butanoyl-DL-homoserine lactone Chemical Structure

N-Butanoyl-DL-homoserine lactone Chemical Structure

CAS No. : 98426-48-3

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10 mM * 1 mL in DMSO
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Based on 1 publication(s) in Google Scholar

Other Forms of N-Butanoyl-DL-homoserine lactone:

N-Butanoyl-DL-homoserine lactone Related Antibodies

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Description

N-Butanoyl-DL-homoserine lactone ((Rac)-C4-HSL) is a racemic mixture of N-Butanoyl-D-homoserine lactone and N-Butanoyl-L-homoserine lactone. N-Butanoyl-L-homoserine lactone is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). N-Butanoyl-L-homoserine lactone has antibacterial activity and is used in antibacterial biofilm. N-Butanoyl-L-homoserine lactone aptamers blocks qurom sensing and inhibits biofilm formation in Pseudomonas aeruginosa[1][2].

Molecular Weight

171.19

Formula

C8H13NO3
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

CCCC(NC1C(OCC1)=O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (584.15 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 5.8415 mL 29.2073 mL 58.4146 mL
5 mM 1.1683 mL 5.8415 mL 11.6829 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 5.8415 mL 29.2073 mL 58.4146 mL 146.0366 mL
5 mM 1.1683 mL 5.8415 mL 11.6829 mL 29.2073 mL
10 mM 0.5841 mL 2.9207 mL 5.8415 mL 14.6037 mL
15 mM 0.3894 mL 1.9472 mL 3.8943 mL 9.7358 mL
20 mM 0.2921 mL 1.4604 mL 2.9207 mL 7.3018 mL
25 mM 0.2337 mL 1.1683 mL 2.3366 mL 5.8415 mL
30 mM 0.1947 mL 0.9736 mL 1.9472 mL 4.8679 mL
40 mM 0.1460 mL 0.7302 mL 1.4604 mL 3.6509 mL
50 mM 0.1168 mL 0.5841 mL 1.1683 mL 2.9207 mL
60 mM 0.0974 mL 0.4868 mL 0.9736 mL 2.4339 mL
80 mM 0.0730 mL 0.3651 mL 0.7302 mL 1.8255 mL
100 mM 0.0584 mL 0.2921 mL 0.5841 mL 1.4604 mL
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N-Butanoyl-DL-homoserine lactone Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

N-Butanoyl-DL-homoserine lactone98426-48-3(Rac)-C4-HSLBacterialInhibitorinhibitorinhibit

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