N-Methyldopamine hydrochloride

Name: N-Methyldopamine hydrochloride
Brand: MedChemExpress
SKU: HY-W014728
Rating: 4.5 (1 reviews)

Cat. No.: HY-W014728 Purity: 99.03%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

N-Methyldopamine hydrochloride is a precursor of adrenaline in the adrenal medulla. N-Methyldopamine hydrochloride is a modification of the dopamine (DA), and retains agonist activity at the DA1 receptor. N-Methyldopamine hydrochloride remains capable of universal surface coating and secondary reactions using the surface catechols. N-Methyldopamine hydrochloride can be used for heart failure research.

For research use only. We do not sell to patients.

N-Methyldopamine hydrochloride Chemical Structure

CAS No. : 62-32-8

Size	Price	Stock	Quantity
50 mg	USD 75	In-stock	Estimated Time of Arrival: December 31
100 mg	USD 115	In-stock	Estimated Time of Arrival: December 31
250 mg	USD 215	In-stock	Estimated Time of Arrival: December 31
500 mg		Get quote
1 g		Get quote

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Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of N-Methyldopamine hydrochloride:

Deoxy Epinephrine-d3 hydrochloride Get quote

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View All Dopamine Receptor Isoform Specific Products:

View All Isoforms

Dopamine Receptor D₁ Receptor D₂ Receptor D₃ Receptor D₄ Receptor D₅ Receptor

Biological Activity
Purity & Documentation
References
Customer Review

Description

IC₅₀ & Target

D₁ Receptor

In Vitro

N-Methyldopamine hydrochloride shows highly improved surface coating properties, and exhibits an accelerated coating rate. N-Methyldopamine hydrochloride coating makes solid surface cell adhesion possible, and postfunctionalization of the coating is also possible^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

203.67

Formula

C₉H₁₄ClNO₂

CAS No.

62-32-8

Appearance

Solid

Color

Light brown to gray

SMILES

CNCCC1=CC(O)=C(O)C=C1.Cl

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility

In Vitro:

H₂O : ≥ 100 mg/mL (490.99 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	4.9099 mL	24.5495 mL	49.0990 mL
5 mM	0.9820 mL	4.9099 mL	9.8198 mL
10 mM	0.4910 mL	2.4550 mL	4.9099 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

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μL

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

Purity & Documentation

Purity: 99.03%

Select Batch:

Data Sheet (271 KB) SDS (393 KB)

COA (246 KB) HNMR (296 KB) LCMS (86 KB)

Handling Instructions (2659 KB)

References

[1]. Kim Y, et al. Effect of N-Methylation on Dopamine Surface Chemistry. Langmuir. 2022 May 24;38(20):6404-6410. [Content Brief]

[2]. Laduron P. N-Methyldopamine (epinine), a precursor of adrenaline in the adrenal medulla. Arch Int Pharmacodyn Ther. 1972 Apr;196:Suppl 196:304-. [Content Brief]

[3]. Rajfer SI, et al. Effects of long-term therapy with oral ibopamine on resting hemodynamics and exercise capacity in patients with heart failure: relationship to the generation of N-methyldopamine and to plasma norepinephrine levels. Circulation. 1986 Apr; [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

H₂O	1 mM	4.9099 mL	24.5495 mL	49.0990 mL	122.7476 mL
	5 mM	0.9820 mL	4.9099 mL	9.8198 mL	24.5495 mL
	10 mM	0.4910 mL	2.4550 mL	4.9099 mL	12.2748 mL
	15 mM	0.3273 mL	1.6366 mL	3.2733 mL	8.1832 mL
	20 mM	0.2455 mL	1.2275 mL	2.4550 mL	6.1374 mL
	25 mM	0.1964 mL	0.9820 mL	1.9640 mL	4.9099 mL
	30 mM	0.1637 mL	0.8183 mL	1.6366 mL	4.0916 mL
	40 mM	0.1227 mL	0.6137 mL	1.2275 mL	3.0687 mL
	50 mM	0.0982 mL	0.4910 mL	0.9820 mL	2.4550 mL
	60 mM	0.0818 mL	0.4092 mL	0.8183 mL	2.0458 mL
	80 mM	0.0614 mL	0.3069 mL	0.6137 mL	1.5343 mL
	100 mM	0.0491 mL	0.2455 mL	0.4910 mL	1.2275 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.