2. Epigenetics TGF-beta/Smad
  3. PKC
  4. N-myristoyl-RKRTLRRL

N-myristoyl-RKRTLRRL inhibits binding of PKC substrates. N-myristoyl-RKRTLRRL inhibits Ca2+- and phosphatidylserine (PS)-dependent histone phosphorylation with IC50 of 5 μM. histone phosphorylation with IC50 of 80 μM.

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N-myristoyl-RKRTLRRL Chemical Structure

N-myristoyl-RKRTLRRL Chemical Structure

CAS No. : 152246-40-7

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10 mg USD 200 In-stock
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Based on 1 publication(s) in Google Scholar

N-myristoyl-RKRTLRRL Related Antibodies

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PKC PKCα PKCβ PKCγ PKCδ PKCε PKCη PKCζ PKCθ PKCμ PKC-ι ℩ PKCι

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Description

N-myristoyl-RKRTLRRL inhibits binding of PKC substrates. N-myristoyl-RKRTLRRL inhibits Ca2+- and phosphatidylserine (PS)-dependent histone phosphorylation with IC50 of 5 μM. histone phosphorylation with IC50 of 80 μM[1][2].

Molecular Weight

1308.71

Formula

C60H117N21O11
CAS No.
Appearance

Solid

Color

White to off-white

Sequence

{Myr}-Arg-Lys-Arg-Thr-Leu-Arg-Arg-Leu
Sequence Shortening

{Myr}-RKRTLRRL
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : 50 mg/mL (38.21 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.7641 mL 3.8206 mL 7.6411 mL
5 mM 0.1528 mL 0.7641 mL 1.5282 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 0.7641 mL 3.8206 mL 7.6411 mL 19.1028 mL
5 mM 0.1528 mL 0.7641 mL 1.5282 mL 3.8206 mL
10 mM 0.0764 mL 0.3821 mL 0.7641 mL 1.9103 mL
15 mM 0.0509 mL 0.2547 mL 0.5094 mL 1.2735 mL
20 mM 0.0382 mL 0.1910 mL 0.3821 mL 0.9551 mL
25 mM 0.0306 mL 0.1528 mL 0.3056 mL 0.7641 mL
30 mM 0.0255 mL 0.1274 mL 0.2547 mL 0.6368 mL
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N-myristoyl-RKRTLRRL Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

N-myristoyl-RKRTLRRL152246-40-7PKCProtein kinase CPKC inhibitorInhibitorinhibitorinhibit

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