2. Anti-infection
  3. Bacterial
  4. N-Phenylacetyl-L-homoserine lactone

N-Phenylacetyl-L-homoserine lactone 

Cat. No.: HY-137407 Purity: 99.60%
SDS COA Handling Instructions

Molarity Calculator

N-Phenylacetyl-L-homoserine lactone is a small diffusible signaling molecule that strongly antagonizes or super-activates the quorum sensing of Vibrio fischeri.

For research use only. We do not sell to patients.

N-Phenylacetyl-L-homoserine lactone Chemical Structure

N-Phenylacetyl-L-homoserine lactone Chemical Structure

CAS No. : 55154-48-8

Size Price Stock Quantity
1 mg USD 77 In-stock
5 mg USD 270 In-stock
10 mg USD 460 In-stock
25 mg USD 950 In-stock
50 mg   Get quote  
100 mg   Get quote  

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

N-Phenylacetyl-L-homoserine lactone Related Antibodies

Top Publications Citing Use of Products

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

N-Phenylacetyl-L-homoserine lactone is a small diffusible signaling molecule that strongly antagonizes or super-activates the quorum sensing of Vibrio fischeri[1].

Cellular Effect
Cell Line Type Value Description References
NCI-H630 IC50
> 100 μM
Compound: 2, 2-phenylettianoyt-L-HSL
Cytotoxicity against human NCI-H630 cells after 5 days by SRB assay
Cytotoxicity against human NCI-H630 cells after 5 days by SRB assay
[PMID: 19260689]
NCI-H630 IC50
> 100 μM
Compound: 2, 2-phenylettianoyt-L-HSL
Cytotoxicity against 5FU-resistant human NCI-H630 cells after 5 days by SRB assay
Cytotoxicity against 5FU-resistant human NCI-H630 cells after 5 days by SRB assay
[PMID: 19260689]
PC-3 IC50
> 100 μM
Compound: 2, 2-phenylettianoyt-L-HSL
Cytotoxicity against human PC3 cells after 5 days by SRB assay
Cytotoxicity against human PC3 cells after 5 days by SRB assay
[PMID: 19260689]
Molecular Weight

219.24

Formula

C12H13NO3
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C(CC1=CC=CC=C1)N[C@@H](CCO2)C2=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : ≥ 125 mg/mL (570.15 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.5612 mL 22.8061 mL 45.6121 mL
5 mM 0.9122 mL 4.5612 mL 9.1224 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 4.5612 mL 22.8061 mL 45.6121 mL 114.0303 mL
5 mM 0.9122 mL 4.5612 mL 9.1224 mL 22.8061 mL
10 mM 0.4561 mL 2.2806 mL 4.5612 mL 11.4030 mL
15 mM 0.3041 mL 1.5204 mL 3.0408 mL 7.6020 mL
20 mM 0.2281 mL 1.1403 mL 2.2806 mL 5.7015 mL
25 mM 0.1824 mL 0.9122 mL 1.8245 mL 4.5612 mL
30 mM 0.1520 mL 0.7602 mL 1.5204 mL 3.8010 mL
40 mM 0.1140 mL 0.5702 mL 1.1403 mL 2.8508 mL
50 mM 0.0912 mL 0.4561 mL 0.9122 mL 2.2806 mL
60 mM 0.0760 mL 0.3801 mL 0.7602 mL 1.9005 mL
80 mM 0.0570 mL 0.2851 mL 0.5702 mL 1.4254 mL
100 mM 0.0456 mL 0.2281 mL 0.4561 mL 1.1403 mL
  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.

N-Phenylacetyl-L-homoserine lactone Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

N-Phenylacetyl-L-homoserine lactone55154-48-8Bacterialquorum sensingVibrio fischeriInhibitorinhibitorinhibit

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product Name

  

Salutation

Applicant Name *

 

Email Address *

Phone Number *

 

Organization Name *

Department *

 

Requested quantity *

Country or Region *

      

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
N-Phenylacetyl-L-homoserine lactone
Cat. No.:
HY-137407
Quantity:
MCE Japan Authorized Agent:

Customer Review

Thank You for Your Feedback!

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

Product Name

  

Lot #

Applicant Name *

 

Email Address *

Phone Number

 

Department *

Organization Name *

 

Country or Region *

Remarks

SAFETY DATA SHEET (SDS)

English - EN (252 KB) Français - FR (252 KB) Deutsch - DE (252 KB) Norwegian - NO (252 KB) Español - ES (252 KB) Swedish - SV (252 KB)

Request for HNMR Report

We have received your request and will respond to you as soon as possible.