1. Cell Cycle/DNA Damage
  2. Nucleoside Antimetabolite/Analog
  3. N2-iBu-2’,3’-bis-O-TBDMS guanosine

N2-iBu-2’,3’-bis-O-TBDMS guanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.

For research use only. We do not sell to patients.

N2-iBu-2’,3’-bis-O-TBDMS guanosine Chemical Structure

N2-iBu-2’,3’-bis-O-TBDMS guanosine Chemical Structure

CAS No. : 79974-70-2

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Description

N2-iBu-2’,3’-bis-O-TBDMS guanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Molecular Weight

581.85

Formula

C26H47N5O6Si2

CAS No.
SMILES

OC[C@H]1O[C@@H](N(C=N2)C3=C2C(NC(NC(C(C)C)=O)=N3)=O)[C@H](O[Si](C)(C)C(C)(C)C)[C@@H]1O[Si](C)(C)C(C)(C)C

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Room temperature in continental US; may vary elsewhere.

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Please store the product under the recommended conditions in the Certificate of Analysis.

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
N2-iBu-2’,3’-bis-O-TBDMS guanosine
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