N3-Gly-Gly-OH

Cat. No.: HY-151859 Purity: 98.40%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

N3-Gly-Gly-OH is a click chemistry reagent. Click chemistry has great potential for use in binding between nucleic acids, lipids, proteins, and other molecules, and has been used in many research fields because of its beneficial characteristics, including high yield, high specificity, and simplicity. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

For research use only. We do not sell to patients.

N3-Gly-Gly-OH Chemical Structure

CAS No. : 855750-87-7

Size	Price	Stock	Quantity
5 mg	USD 120	In-stock	Estimated Time of Arrival: December 31
10 mg	USD 190	In-stock	Estimated Time of Arrival: December 31
25 mg	USD 350	In-stock	Estimated Time of Arrival: December 31
50 mg		Get quote
100 mg		Get quote

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Other Forms of N3-Gly-Gly-OH:

N3-Gly-Gly-OH (DCHA) Get quote

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References
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Description

N3-Gly-Gly-OH is a click chemistry reagent. Click chemistry has great potential for use in binding between nucleic acids, lipids, proteins, and other molecules, and has been used in many research fields because of its beneficial characteristics, including high yield, high specificity, and simplicity^[1]. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

Molecular Weight

158.12

Formula

C₄H₆N₄O₃

CAS No.

855750-87-7

Appearance

Liquid

Color

Colorless to light yellow

SMILES

[N-]=[N+]=NCC(NCC(O)=O)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Pure form	-20°C	3 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : 250 mg/mL (1581.08 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

H₂O : 125 mg/mL (790.54 mM; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	6.3243 mL	31.6216 mL	63.2431 mL
5 mM	1.2649 mL	6.3243 mL	12.6486 mL
10 mM	0.6324 mL	3.1622 mL	6.3243 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

Purity & Documentation

Purity: 98.40%

Select Batch:

Data Sheet (267 KB) SDS (251 KB)

COA (242 KB) HNMR (224 KB) LCMS (88 KB)

Handling Instructions (2659 KB)

References

[1]. Jiang X, et al. Recent applications of click chemistry in drug discovery. Expert Opin Drug Discov. 2019 Aug;14(8):779-789. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

H₂O / DMSO	1 mM	6.3243 mL	31.6216 mL	63.2431 mL	158.1078 mL
	5 mM	1.2649 mL	6.3243 mL	12.6486 mL	31.6216 mL
	10 mM	0.6324 mL	3.1622 mL	6.3243 mL	15.8108 mL
	15 mM	0.4216 mL	2.1081 mL	4.2162 mL	10.5405 mL
	20 mM	0.3162 mL	1.5811 mL	3.1622 mL	7.9054 mL
	25 mM	0.2530 mL	1.2649 mL	2.5297 mL	6.3243 mL
	30 mM	0.2108 mL	1.0541 mL	2.1081 mL	5.2703 mL
	40 mM	0.1581 mL	0.7905 mL	1.5811 mL	3.9527 mL
	50 mM	0.1265 mL	0.6324 mL	1.2649 mL	3.1622 mL
	60 mM	0.1054 mL	0.5270 mL	1.0541 mL	2.6351 mL
	80 mM	0.0791 mL	0.3953 mL	0.7905 mL	1.9763 mL
	100 mM	0.0632 mL	0.3162 mL	0.6324 mL	1.5811 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

N3-Gly-Gly-OH Related Classifications

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Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

N3-Gly-Gly-OH855750-87-7ADC LinkerAntibody-drug conjugates linkerclick chemistryhigh yieldhigh specificitysimplicitybindingInhibitorinhibitorinhibit

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