2. Anti-infection
  3. Influenza Virus
  4. Neuraminidase-IN-2

Neuraminidase-IN-2 is an anti-influenza compounds with IC50 values of 0.28, 0.27, 11.50, 0.089 and 23.44 µM for H1N1, 09H1N1, H3N2, H5N1 and H5N2, respectively. Neuraminidase-IN-2 has antiviral activity and low cytotoxicity.

For research use only. We do not sell to patients.

Neuraminidase-IN-2 Chemical Structure

Neuraminidase-IN-2 Chemical Structure

CAS No. : 2599015-44-6

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Neuraminidase-IN-2 Related Antibodies

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Description

Neuraminidase-IN-2 is an anti-influenza compounds with IC50 values of 0.28, 0.27, 11.50, 0.089 and 23.44 µM for H1N1, 09H1N1, H3N2, H5N1 and H5N2, respectively. Neuraminidase-IN-2 has antiviral activity and low cytotoxicity[1].

Cellular Effect
Cell Line Type Value Description References
MDCK CC50
> 250 μM
Compound: 5c
Cytotoxicity against MDCK cells assessed as reduction in cell viability by MTT assay
Cytotoxicity against MDCK cells assessed as reduction in cell viability by MTT assay
[PMID: 33385836]
In Vivo

Neuraminidase-IN-2 (Compound 5c) (1 g/kg; i.g.; single dose) shows low toxicity to mice and insignificantly increases the weight of mouse[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Molecular Weight

510.62

Formula

C29H38N2O6
CAS No.
SMILES

COC1=CC(COC2=CC=C(CN[C@@H]3[C@@H](NC(C)=O)[C@H](OC(CC)CC)C=C(C(O)=O)C3)C=C2)=CC=C1
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Neuraminidase-IN-2 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Neuraminidase-IN-22599015-44-6Influenza VirusAntiviral activityLow cytotoxicityInhibitorinhibitorinhibit

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