2. Immunology/Inflammation
  3. NOD-like Receptor (NLR)
  4. NLRP3-IN-57

NLRP3-IN-57 (compound 5) inhibits the NLRP3 inflammasome, thereby reducing IL-1β levels in LPS plus Nigericin-induced THP-1 macrophages.

For research use only. We do not sell to patients.

NLRP3-IN-57 Chemical Structure

NLRP3-IN-57 Chemical Structure

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NLRP3-IN-57 Related Antibodies

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Description

NLRP3-IN-57 (compound 5) inhibits the NLRP3 inflammasome, thereby reducing IL-1β levels in LPS plus Nigericin-induced THP-1 macrophages.

Molecular Weight

700.94

Formula

C44H60O7
SMILES

COC(C)(/C=C/C/C(C)=C/C[C@@H]1C[C@]2(C(C(C(C3=CC(O)=C(C=C3)O)=O)=C([C@](C2=O)([C@]1(CC/C=C(C)/C)C)C/C=C(C)\C)O)=O)C/C=C(C)\C)C
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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NLRP3-IN-57 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

NLRP3-IN-57NOD-like Receptor (NLR)Inhibitorinhibitorinhibit

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