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NOC-5 is a diazeniumdiolate compound that belongs to the same family of NO donors.

For research use only. We do not sell to patients.

NOC-5 Chemical Structure

NOC-5 Chemical Structure

CAS No. : 146724-82-5

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Based on 1 publication(s) in Google Scholar

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Description

NOC-5 is a diazeniumdiolate compound that belongs to the same family of NO donors[1].

In Vitro

NOC-5 (5-20 μM) in PBS led to a rapid increase in NO release on day one[1].
NOC-5 (100 μM, 24 h) activates only caspase-3; an increase in caspase-3 activity occurred after NO donor treatment: 1.62 (1.57-1.66) (P < 0.05). NOC-5 has pro-apoptotic action in Jurkat cells, but at the same time increased the level of anti-apoptotic proteins[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

176.22

Formula

C6H16N4O2

CAS No.
Appearance

Solid

Color

Light yellow to yellow

SMILES

CC(N(CCCN)N(N=O)O)C

Shipping

Shipping with dry ice.

Storage

-80°C

Purity & Documentation

Purity: 98.50%

References
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    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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NOC-5
Cat. No.:
HY-126166
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