Norfloxacin (nicotinate) (Synonyms: MK-0366 (nicotinate))

Cat. No.: HY-B0132B: FAQs
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Norfloxacin nicotinate (MK-0366 nicotinate) is a fluoroquinolones antibiotic, an adduct of Norfloxacin (NOR) and nicotinic acid. Norfloxacin nicotinate has been widely used for replacing NOR in animal husbandry and fishery industry. Norfloxacin nicotinate can induce innate immune response at a high concentration.

For research use only. We do not sell to patients.

Norfloxacin (nicotinate) Chemical Structure

CAS No. : 118803-81-9

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Other In-stock Forms of Norfloxacin (nicotinate):

Norfloxacin

Other Forms of Norfloxacin (nicotinate):

Norfloxacin In-stock
Norfloxacin hydrochloride Get quote

3 Publications Citing Use of MCE Norfloxacin (nicotinate)

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Description

IC₅₀ & Target

Quinolone

In Vivo

Norfloxacin nicotinate (5 and/or 25 mg/L) significantly induces antioxidant enzymes activities and the mRNA levels of genes related to antioxidant enzymes and innate immune system in zebrafish larvae^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Clinical Trial

Molecular Weight

442.44

Formula

C₂₂H₂₃FN₄O₅

CAS No.

118803-81-9

SMILES

O=C(C1=CN(CC)C2=C(C=C(F)C(N3CCNCC3)=C2)C1=O)O.O=C(C4=CC=CN=C4)O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Liang X, et al. Effects of norfloxacin nicotinate on the early life stage of zebrafish (Danio rerio): Developmental toxicity, oxidative stress and immunotoxicity. Fish Shellfish Immunol. 2020 Jan;96:262-269. [Content Brief]

Norfloxacin (nicotinate) Related Classifications

Infection

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)	×	Volume _(start)	=	Concentration _(final)	×	Volume _(final)
	×		=		×
C1		V1		C2		V2

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Norfloxacin (nicotinate)118803-81-9MK-0366 (nicotinate)BacterialAntibioticfluoroquinolonesantibacterialinnate immuneInhibitorinhibitorinhibit

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