1. GPCR/G Protein
  2. Bradykinin Receptor
  3. NPC 17731

NPC 17731 is a new bradykinin (BK) receptor antagonist. NPC 17731 antagonized both the contractile and relaxant responses caused by BK in longitudinal smooth muscle with IC50 of 23 and 29 nM, respectively.

For research use only. We do not sell to patients.

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NPC 17731 Chemical Structure

NPC 17731 Chemical Structure

CAS No. : 147267-10-5

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Description

NPC 17731 is a new bradykinin (BK) receptor antagonist. NPC 17731 antagonized both the contractile and relaxant responses caused by BK in longitudinal smooth muscle with IC50 of 23 and 29 nM, respectively[1].

Molecular Weight

1294.50

Formula

C59H95N19O14

CAS No.
Sequence

Arg-Arg-Pro-{Hyp}-Gly-Phe-Ser-{Hyp}-{Oic}-Arg

Sequence Shortening

RRP-{Hyp}-GFS-{Hyp}-{Oic}-R

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
NPC 17731
Cat. No.:
HY-P1721
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