2. PROTAC Vitamin D Related/Nuclear Receptor
  3. PROTACs Nuclear Hormone Receptor 4A/NR4A
  4. NR-V04

NR-V04 is a PROTAC based NR4A1 degrader (Red: NR4A1 inhibitor (HY-13067), black: linker, Blue: E3 ligase ligand).

For research use only. We do not sell to patients.

NR-V04 Chemical Structure

NR-V04 Chemical Structure

CAS No. : 2766608-52-8

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NR-V04 Related Antibodies

Top Publications Citing Use of Products

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von Hippel-Lindau (VHL) Cereblon MDM2 cIAP1

View All Nuclear Hormone Receptor 4A/NR4A Isoform Specific Products:

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Nurr1/NR4A2 Nur77/NR4A1

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Description

NR-V04 is a PROTAC based NR4A1 degrader (Red: NR4A1 inhibitor (HY-13067), black: linker, Blue: E3 ligase ligand)[1].

Molecular Weight

1110.45

Formula

C62H87N5O11S
CAS No.
SMILES

C[C@@]12[C@]([C@@]3([H])[C@@](CC1)(CC[C@](C)(C3)C(NCCOCCOCCOCCOCC(N[C@@H](C(C)(C)C)C(N4[C@@H](C[C@H](C4)O)C(N[C@H](C5=CC=C(C6=C(N=CS6)C)C=C5)C)=O)=O)=O)=O)C)(CC[C@@]7(C2=CC=C8C7=CC(C(O)=C8C)=O)C)C
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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NR-V04 Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

NR-V042766608-52-8PROTACsNuclear Hormone Receptor 4A/NR4ANerve Growth Factor IB-like ReceptorNR4A1protacInhibitorinhibitorinhibit

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