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  4. NSC363998 free base

NSC363998 (free base) is an orally active compound. NSC363998 (free base) can suppress rCGG90 induced neurotoxicity. NSC363998 (free base) can be used for the research of neurodegenerative disorder such as Fragile X associated tremor/ataxia syndrome (FXTAS).

For research use only. We do not sell to patients.

NSC363998 free base Chemical Structure

NSC363998 free base Chemical Structure

CAS No. : 159357-82-1

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NSC363998 free base Related Antibodies

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Description

NSC363998 (free base) is an orally active compound. NSC363998 (free base) can suppress rCGG90 induced neurotoxicity. NSC363998 (free base) can be used for the research of neurodegenerative disorder such as Fragile X associated tremor/ataxia syndrome (FXTAS)[1].

In Vivo

NSC363998 (free base) (oral; 0, 5 μM) can suppress rCGG90 induced neurotoxicity[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: FXTAS Drosophila model[1]
Dosage: 0, 5 μM
Administration: Oral (dissolved in DMSO and added to standard food)
Result: Could modify ommatidial degeneration and diminished neddylation activity in the FXTAS Drosophila model.
Molecular Weight

440.54

Formula

C24H32N4O4
CAS No.
SMILES

O=C1C2=C(C(C3=C1C(NCCCNCCO)=CC=C3)=O)C(NCCCNCCO)=CC=C2
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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NSC363998 free base Related Classifications

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Keywords:

NSC363998159357-82-1NSC 363998NSC-363998OthersoralrCGG90neurotoxicityneurodegenerative disorderFragile X associated tremor/ataxia syndrome (FXTAS)Inhibitorinhibitorinhibit

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