NSC363998 (free base) is an orally active compound.

For research use only. We do not sell to patients.

NSC363998 free base Chemical Structure

Chemical Structure

CAS No. : 159357-82-1

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Based on 1 publication(s) in Google Scholar

NSC363998 free base Related Antibodies

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Description

NSC363998 (free base) is an orally active compound. NSC363998 (free base) can suppress rCGG90 induced neurotoxicity. NSC363998 (free base) can be used for the research of neurodegenerative disorder such as Fragile X associated tremor/ataxia syndrome (FXTAS)[1]. In Vivo: NSC363998 (free base) (oral; 0, 5 μM) can suppress rCGG90 induced neurotoxicity[1].

In Vivo
Animal Model: FXTAS Drosophila model[1]
Dosage: 0, 5 μM
Administration: Oral (dissolved in DMSO and added to standard food)
Result: Could modify ommatidial degeneration and diminished neddylation activity in the FXTAS Drosophila model.
Molecular Weight

440.54

Formula

C24H32N4O4
CAS No.
SMILES

O=C1C2=C(C(C3=C1C(NCCCNCCO)=CC=C3)=O)C(NCCCNCCO)=CC=C2
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Room temperature in continental US; may vary elsewhere.
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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NSC363998 free base
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