1. Cell Cycle/DNA Damage Membrane Transporter/Ion Channel
  2. p97 ATP Synthase
  3. NSC799462

NSC799462 is a triazole inhibitor of p97 ATPase. NSC799462 inhibits p97 ATPase activity (IC50 = 15 nM) by binding to a specific site on p97 and causing local changes in the p97 structure.

For research use only. We do not sell to patients.

NSC799462 Chemical Structure

NSC799462 Chemical Structure

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Description

NSC799462 is a triazole inhibitor of p97 ATPase. NSC799462 inhibits p97 ATPase activity (IC50 = 15 nM) by binding to a specific site on p97 and causing local changes in the p97 structure[1].

IC50 & Target

IC50: 15 nM (p97 ATPase)[1].

Molecular Weight

594.68

Formula

C30H32F2N6O3S

SMILES

O=C(NC1CCN(C)CC1)OCC#CC2=C(F)C=C(OCC3=NN=C(S[C@H]4C=CCCC4)N3C5=CN=CC=C5)C=C2F

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
NSC799462
Cat. No.:
HY-168005
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