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  3. Fluorescent Dye
  4. NTPAN-MI

NTPAN-MI is a fluorescent probe. NTPAN-MI is selectively activated upon labeling unfolded proteins with exposed thiols, thereby reporting on the extent of proteostasis.

For research use only. We do not sell to patients.

NTPAN-MI Chemical Structure

NTPAN-MI Chemical Structure

CAS No. : 2411398-95-1

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1 mg USD 111 In-stock
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Based on 1 publication(s) in Google Scholar

NTPAN-MI Related Antibodies

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Description

NTPAN-MI is a fluorescent probe. NTPAN-MI is selectively activated upon labeling unfolded proteins with exposed thiols, thereby reporting on the extent of proteostasis[1].

Molecular Weight

462.54

Formula

C29H26N4O2
CAS No.
Appearance

Solid

Color

Yellow to orange

SMILES

N#C/C(C1=CC=C(N2C(C=CC2=O)=O)C=C1)=C(C3=CC=C(N(C)C)C=C3)\C4=CC=C(N(C)C)C=C4
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : 25 mg/mL (54.05 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.1620 mL 10.8099 mL 21.6198 mL
5 mM 0.4324 mL 2.1620 mL 4.3240 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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mg/kg

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g

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(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.1620 mL 10.8099 mL 21.6198 mL 54.0494 mL
5 mM 0.4324 mL 2.1620 mL 4.3240 mL 10.8099 mL
10 mM 0.2162 mL 1.0810 mL 2.1620 mL 5.4049 mL
15 mM 0.1441 mL 0.7207 mL 1.4413 mL 3.6033 mL
20 mM 0.1081 mL 0.5405 mL 1.0810 mL 2.7025 mL
25 mM 0.0865 mL 0.4324 mL 0.8648 mL 2.1620 mL
30 mM 0.0721 mL 0.3603 mL 0.7207 mL 1.8016 mL
40 mM 0.0540 mL 0.2702 mL 0.5405 mL 1.3512 mL
50 mM 0.0432 mL 0.2162 mL 0.4324 mL 1.0810 mL
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NTPAN-MI Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

NTPAN-MI2411398-95-1Fluorescent DyeInhibitorinhibitorinhibit

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