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NTPO  (Synonyms: Nitrilotris(methylenephosphonic acid))

Cat. No.: HY-W011425
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NTPO (Nitrilotris methylenephosphonic acid) is a DNA damage inducer, causing genomic DNA damage and fragmentation, activating ATR-mediated cell cycle checkpoints. The DNA damaging effects of NTPO are abrogated by base excision repair (BER) but not nucleotide excision repair (NER).

For research use only. We do not sell to patients.

NTPO Chemical Structure

NTPO Chemical Structure

CAS No. : 6419-19-8

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Other Forms of NTPO:

NTPO Related Antibodies

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Description

NTPO (Nitrilotris methylenephosphonic acid) is a DNA damage inducer, causing genomic DNA damage and fragmentation, activating ATR-mediated cell cycle checkpoints. The DNA damaging effects of NTPO are abrogated by base excision repair (BER) but not nucleotide excision repair (NER)[1].

Molecular Weight

299.05

Formula

C3H12NO9P3
CAS No.
Appearance

Liquid

SMILES

OP(CN(CP(O)(O)=O)CP(O)(O)=O)(O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Pure form -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Purity & Documentation
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NTPO Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

NTPO6419-19-8Nitrilotris(methylenephosphonic acid)OthersATRDNA damage responsePARP1circadian clocknon-thermal plasmaInhibitorinhibitorinhibit

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