NTPO trisodium (Synonyms: Nitrilotris(methylenephosphonic acid), trisodium salt)

Cat. No.: HY-W011425A: Data Sheet Handling Instructions Technical Support

NTPO trisodium is a DNA damage inducer, causing genomic DNA damage and fragmentation, activating ATR-mediated cell cycle checkpoints. The DNA damaging effects of NTPO trisodium are abrogated by base excision repair (BER) but not nucleotide excision repair (NER).

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NTPO trisodium Chemical Structure

CAS No. : 7611-50-9

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Other Forms of NTPO trisodium:

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Description	NTPO trisodium is a DNA damage inducer, causing genomic DNA damage and fragmentation, activating ATR-mediated cell cycle checkpoints. The DNA damaging effects of NTPO trisodium are abrogated by base excision repair (BER) but not nucleotide excision repair (NER)^[1].
Molecular Weight	365.00
Formula	C₃H₉NNa₃O₉P₃
CAS No.	7611-50-9
SMILES	O=P(CN(CP(O)(O[Na])=O)CP(O)(O[Na])=O)(O[Na])O
Shipping	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation	Data Sheet (271 KB) Handling Instructions (2659 KB)
References	[1]. Choi JY, et al. Non-thermal plasma-induced apoptosis is modulated by ATR- and PARP1-mediated DNA damage responses and circadian clock. Oncotarget. 2016 May 31;7(22):32980-9. [Content Brief]

NTPO trisodium Related Classifications

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass		Concentration		Volume		Molecular Weight *
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The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)	×	Volume _(start)	=	Concentration _(final)	×	Volume _(final)
	×		=		×
C1		V1		C2		V2

Keywords:

NTPO trisodium7611-50-9Nitrilotris(methylenephosphonic acid), trisodiumOthersATRDNA damage responsePARP1circadian clocknon-thermal plasmaInhibitorinhibitorinhibit

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NTPO trisodium (Synonyms: Nitrilotris(methylenephosphonic acid), trisodium salt)

Other Forms of NTPO trisodium:

Biological Activity

Purity & Documentation

References

Customer Review

NTPO trisodium Related Classifications

Molarity Calculator

Dilution Calculator